The deep cerebellar nuclei (DCN) are at the center of the cerebellum not only anatomically but also functionally. Classical anatomical studies have described different types of DCN …
An unusual feature of the cerebellar cortex is that its output neurons, Purkinje cells, release GABA (γ-aminobutyric acid). Their high intrinsic firing rates (50 Hz) and extensive …
AS Saab, A Neumeyer, HM Jahn, A Cupido… - Science, 2012 - science.org
The impact of glial neurotransmitter receptors in vivo is still elusive. In the cerebellum, Bergmann glial (BG) cells express α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid …
Behavioral and computational studies predict that synaptic plasticity of excitatory mossy fiber inputs to cerebellar nuclear neurons is required for associative learning, but standard …
V Gauck, D Jaeger - Journal of Neuroscience, 2000 - Soc Neuroscience
Cerebellar nucleus neurons were recorded in vitro, and dynamic clamping was used to simulate inhibitory synaptic input from Purkinje cells likely to occur in vivo. Inhibitory input …
Y Zhang, RR Llinas, J Lisman - Frontiers in neural circuits, 2009 - frontiersin.org
Injection of NMDAR antagonist into the thalamus can produce delta frequency EEG oscillations in the thalamocortical system. It is surprising that an antagonist of an excitatory …
P Telgkamp, IM Raman - Journal of Neuroscience, 2002 - Soc Neuroscience
Neurons of the cerebellar nuclei have basal firing rates of 10–20 Hz, despite the convergence of many GABAergic Purkinje terminals onto cerebellar nuclear somata and the …
N Zheng, IM Raman - The Cerebellum, 2010 - Springer
Neurons of the cerebellar nuclei generate the non-vestibular output of the cerebellum. Like other neurons, they integrate excitatory and inhibitory synaptic inputs and filter them through …
JR Pugh, IM Raman - Journal of Neuroscience, 2008 - Soc Neuroscience
Neurons of the cerebellar nuclei receive synaptic excitation from cerebellar mossy fibers. Unlike in many principal neurons, coincident presynaptic activity and postsynaptic …