Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy

AA Bhat, S Nisar, S Maacha, TC Carneiro-Lobo… - Molecular cancer, 2021 - Springer
Esophageal cancer (EC) is a disease often marked by aggressive growth and poor
prognosis. Lack of targeted therapies, resistance to chemoradiation therapy, and distant …

Ten-year outcome of neoadjuvant chemoradiotherapy plus surgery for esophageal cancer: the randomized controlled CROSS trial

BM Eyck, JJB van Lanschot, MCCM Hulshof… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Preoperative chemoradiotherapy according to the chemoradiotherapy for
esophageal cancer followed by surgery study (CROSS) has become a standard of care for …

Immunotherapy for esophageal cancer: state-of-the art in 2021

H Teixeira Farinha, A Digklia, D Schizas, N Demartines… - Cancers, 2022 - mdpi.com
Simple Summary The aim of this review was to describe the rationale for immunotherapy in
different stages of esophageal cancer (EC) treatment, with a particular accent on curative …

Trastuzumab in combination with 5‐fluorouracil, leucovorin, oxaliplatin and docetaxel as perioperative treatment for patients with human epidermal growth factor …

RD Hofheinz, S Hegewisch‐Becker… - … Journal of Cancer, 2021 - Wiley Online Library
Perioperative chemotherapy with 5‐fluorouracil, leucovorin, oxaliplatin and docetaxel
(FLOT) is a mainstay in the treatment of esophagogastric adenocarcinomas (EGA) …

FLOT versus FLOT/Trastuzumab/Pertuzumab perioperative therapy of human epidermal growth factor receptor 2–positive resectable esophagogastric …

RD Hofheinz, K Merx, GM Haag… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE High pathologic complete response (pCR) rates and comparably good survival
data were seen in a phase II trial combining perioperative fluorouracil, leucovorin …

Self-targeting platinum (IV) amphiphilic prodrug nano-assembly as radiosensitizer for synergistic and safe chemoradiotherapy of hepatocellular carcinoma

X Xiao, Y Wang, J Chen, P Qin, P Chen, D Zhou, Y Pan - Biomaterials, 2022 - Elsevier
Chemoradiotherapy is a widely used treatment for patients with malignancies such as
hepatocellular carcinoma (HCC). However, it remains challenging to realize safe and …

X‐ray excited luminescence materials for cancer diagnosis and theranostics

Q Ma, Y Cao, X Ge, Z Zhang, S Gao… - Laser & Photonics …, 2024 - Wiley Online Library
X‐rays are rays that penetrate the human tissue and are capable of penetrating water, air,
and oxygen in various biological tissues or tumors. In recent years, significant progress has …

The history and development of HER2 inhibitors

X Xia, C Gong, Y Zhang, H Xiong - Pharmaceuticals, 2023 - mdpi.com
HER2 is highly expressed in a variety of malignant tumors and affects the prognosis of
patients, making it a highly sensitive target for cancer therapy. Since the approval of the first …

[HTML][HTML] Comparative genomic analysis of esophageal squamous cell carcinoma and adenocarcinoma: new opportunities towards molecularly targeted therapy

X Zhang, Y Wang, L Meng - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Esophageal cancer is one of the most lethal cancers worldwide because of its rapid
progression and poor prognosis. Esophageal squamous cell carcinoma (ESCC) and …

Impact of pathological tumor response after CROSS neoadjuvant chemoradiotherapy followed by surgery on long-term outcome of esophageal cancer: a population …

A Al-Kaabi, RS van der Post, LR van der Werf… - Acta …, 2021 - Taylor & Francis
Background With increasing interest in organ-preserving strategies for potentially curable
esophageal cancer, real-world data is needed to understand the impact of pathological …