The role of IgLON cell adhesion molecules in neurodegenerative diseases

M Salluzzo, C Vianello, S Abdullatef, R Rimondini… - Genes, 2023 - mdpi.com
In the brain, cell adhesion molecules (CAMs) are critical for neurite outgrowth, axonal
fasciculation, neuronal survival and migration, and synapse formation and maintenance …

miR-122/NEGR1 axis contributes colorectal cancer liver metastasis by PI3K/AKT pathway and macrophage modulation

S Dai, H Zhuang, Z Li, Z Chen, Y Chai… - Journal of Translational …, 2024 - Springer
Colorectal cancer (CRC) is a prevalent malignant tumor in the gastrointestinal tract, with
around 50% of patients experiencing distant metastases, predominantly to the liver …

The IgLON family of cell adhesion molecules expressed in developing neural circuits ensure the proper functioning of the sensory system in mice

K Singh, M Jayaram, A Hanumantharaju, T Tõnissoo… - Scientific Reports, 2024 - nature.com
Deletions and malfunctions of the IgLON family of cell adhesion molecules are associated
with anatomical, behavioral, and metabolic manifestations of neuropsychiatric disorders. We …

[HTML][HTML] A cost-effective and efficient ex vivo, ex situ human whole brain perfusion protocol for immunohistochemistry

AC Hade, MA Philips, L Promet, T Jagomäe… - Journal of Neuroscience …, 2024 - Elsevier
Background Chemical fixation of the brain can be executed through either the immersion
method or the perfusion method. Perfusion fixation allows for better preservation of the brain …

Dissecting shared genetic architecture between depression and body mass index

H Zhang, R Zheng, B Yu, Y Yu, X Luo, S Yin, Y Zheng… - BMC medicine, 2024 - Springer
Background A growing body of evidence supports the comorbidity between depression
(DEP) and obesity, yet the genetic mechanisms underlying this association remain unclear …

[HTML][HTML] Is There a Natural, Non-addictive, and Non-anti-reward, Safe, Gene-based Solution to Treat Reward Deficiency Syndrome? KB220 Variants vs GLP-1 …

EJ Modestino, A Bowirrat, D Baron… - Journal of addiction …, 2024 - pmc.ncbi.nlm.nih.gov
Reward deficiency syndrome (RDS) is an umbrella term encompassing a wide array of
addictive behaviors that affect individuals across diverse spectra of society. Our research …