[HTML][HTML] Spatially resolved transcriptomics: a comprehensive review of their technological advances, applications, and challenges

M Cheng, Y Jiang, J Xu, AFA Mentis, S Wang… - Journal of Genetics and …, 2023 - Elsevier
The ability to explore life kingdoms is largely driven by innovations and breakthroughs in
technology, from the invention of the microscope 350 years ago to the recent emergence of …

[HTML][HTML] Single cell spatial biology over developmental time can decipher pediatric brain pathologies

R Nussinov, BR Yavuz, H Jang - Neurobiology of Disease, 2024 - Elsevier
Pediatric low grade brain tumors and neurodevelopmental disorders share proteins,
signaling pathways, and networks. They also share germline mutations and an impaired …

[HTML][HTML] Resolving the gene expression maps of human first-trimester chorionic villi with spatial transcriptome

Z Liu, M Zhai, Q Zhang, T Yang, Z Wan, J Li… - Frontiers in Cell and …, 2022 - frontiersin.org
The placenta is important for fetal development in mammals, and spatial transcriptomic
profiling of placenta helps to resolve its structure and function. In this study, we described the …

[HTML][HTML] Patterning the cerebral cortex into distinct functional domains during development

D Appan, SM Hsu, WH Hsu, SJ Chou - Current Opinion in Neurobiology, 2023 - Elsevier
The cerebral cortex is compartmentalized into multiple regions, including the newly evolved
neocortex and evolutionarily older paleocortex and archicortex. These broad cortical regions …

Spatially resolved molecular and cellular atlas of the mouse brain

L Han, Z Liu, Z Jing, Y Liu, H Chang, J Lei, Y Peng… - bioRxiv, 2023 - biorxiv.org
A comprehensive atlas of genes, cell types, and their spatial distribution across a whole
mammalian brain is fundamental for understanding function of the brain. Here, using snRNA …

[HTML][HTML] Emergence of neuron types

L Faure, P Techameena, S Hadjab - Current Opinion in Cell Biology, 2022 - Elsevier
Neuron types are the building blocks of the nervous system, and therefore, of functional
circuits. Understanding the origin of neuronal diversity has always been an essential …