The dorsal striatum is organized into functional territories defined by corticostriatal inputs
onto both direct and indirect spiny projection neurons (SPNs), the major cell types within the …

Huntington's disease is a neurodegenerative disorder caused by a CAG repeat expansion in
exon 1 of the huntingtin gene. Striatal projection neurons are mainly affected, leading to …

In the auditory cortex, synaptic plasticity, including long-term potentiation (LTP) and long-
term depression (LTD), plays crucial roles in information processing and adaptation to the …

In early Alzheimer disease (AD) models synaptic failures and upstreaming aberrant patterns
of network synchronous activity result in hippocampal-dependent memory deficits. In such …

Background Repetitive negative thinking (RNT), often referred to as rumination in the mood
disorders literature, is a symptom dimension associated with poor prognosis and suicide in …

Objective Deep brain stimulation (DBS) is an increasingly applied treatment for various
neuropsychiatric disorders including drug‐resistant epilepsy, and it may be optimized by …

Myogenesis is the biological process by which skeletal muscle tissue forms. Regulation of
myogenesis involves a variety of conventional, epigenetic, and epigenomic mechanisms …

The basal ganglia (BG) are involved in cognitive/motivational functions in addition to
movement control. Thus, BG segregated circuits, the sensorimotor (SM) and medial …

How do animals adopt a given behavioral strategy to solve a recurrent problem when
several effective strategies are available to reach the goal? Here we provide evidence that …

Invasive brain stimulation has emerged as an alternative treatment for refractory epilepsy
patients and an increasing number of trials evaluating its efficacy and safety have been …