Exosomes in angiogenesis and anti-angiogenic therapy in cancers
W Olejarz, G Kubiak-Tomaszewska… - International Journal of …, 2020 - mdpi.com
Angiogenesis is the process through which new blood vessels are formed from pre-existing
ones. Exosomes are involved in angiogenesis in cancer progression by transporting …
ones. Exosomes are involved in angiogenesis in cancer progression by transporting …
The endothelial tip-stalk cell selection and shuffling during angiogenesis
W Chen, P Xia, H Wang, J Tu, X Liang… - Journal of cell …, 2019 - Springer
Angiogenesis is a critical, fine-tuned, multi-staged biological process. Tip-stalk cell selection
and shuffling are the building blocks of sprouting angiogenesis. Accumulated evidences …
and shuffling are the building blocks of sprouting angiogenesis. Accumulated evidences …
Mimicking the natural basement membrane for advanced tissue engineering
Advancements in the field of tissue engineering have led to the elucidation of physical and
chemical characteristics of physiological basement membranes (BM) as specialized forms of …
chemical characteristics of physiological basement membranes (BM) as specialized forms of …
Understanding the principles of pattern formation driven by notch signaling by integrating experiments and theoretical models
Notch signaling is an evolutionary conserved cell-cell communication pathway. Besides
regulating cell-fate decisions at an individual cell level, Notch signaling coordinates the …
regulating cell-fate decisions at an individual cell level, Notch signaling coordinates the …
An in vitro model of the macrophage-endothelial interface to characterize CAR T-cell induced cytokine storm
Abstract Chimeric Antigen Receptor (CAR) T-cell therapy is a highly effective treatment for B-
cell malignancies but limited in use due to clinically significant hyperinflammatory toxicities …
cell malignancies but limited in use due to clinically significant hyperinflammatory toxicities …
Systems biology of angiogenesis signaling: Computational models and omics
Angiogenesis is a highly regulated multiscale process that involves a plethora of cells, their
cellular signal transduction, activation, proliferation, differentiation, as well as their …
cellular signal transduction, activation, proliferation, differentiation, as well as their …
[HTML][HTML] Personalization of logical models with multi-omics data allows clinical stratification of patients
Logical models of cancer pathways are typically built by mining the literature for relevant
experimental observations. They are usually generic as they apply for large cohorts of …
experimental observations. They are usually generic as they apply for large cohorts of …
Targeting angiogenesis in myocardial infarction: Novel therapeutics
J Li, Y Zhao, W Zhu - Experimental and therapeutic …, 2022 - spandidos-publications.com
Acute myocardial infarction (AMI) remains the main cause of mortality worldwide. Despite
surgery and medical treatment, the non‑regeneration of dead cardiomyocytes and the …
surgery and medical treatment, the non‑regeneration of dead cardiomyocytes and the …
Decoding dysregulated angiogenesis in HTLV-1 asymptomatic carriers compared to healthy individuals
Human T-cell lymphotropic virus type 1 (HTLV-1) is the first identified human retrovirus
responsible for two significant diseases: HTLV-1-associated myelopathy/tropical spastic …
responsible for two significant diseases: HTLV-1-associated myelopathy/tropical spastic …
Endothelial senescence and its impact on angiogenesis in Alzheimer's disease
Endothelial cells are constantly exposed to environmental stress factors that, above a certain
threshold, trigger cellular senescence and apoptosis. The altered vascular function affects …
threshold, trigger cellular senescence and apoptosis. The altered vascular function affects …