Obstructive sleep apnea (OSA) is thought to affect almost 1 billion people worldwide. OSA
has well established cardiovascular and neurocognitive sequelae, although the optimal …

Atherosclerotic cardiovascular disease (CVD) is a chronic disorder developing insidiously
throughout life and usually progressing to an advanced stage by the time symptoms occur. It …

Obstructive sleep apnea (OSA) is probably the most common respiratory disorder, with
recent data from the United States and Europe suggesting that between 14% and 49% of …

Sleep-induced apnea and disordered breathing refers to intermittent, cyclical cessations or
reductions of airflow, with or without obstructions of the upper airway (OSA). In the presence …

Background—Clinic-based observational studies in men have reported that obstructive
sleep apnea is associated with an increased incidence of coronary heart disease. The …

Population-based epidemiologic studies have uncovered the high prevalence and wide
severity spectrum of undiagnosed obstructive sleep apnea, and have consistently found that …

Background The effect of obstructive sleep apnoea-hypopnoea as a cardiovascular risk
factor and the potential protective effect of its treatment with continuous positive airway …

Background Sleep-disordered breathing is a common condition associated with adverse
health outcomes including hypertension and cardiovascular disease. The overall objective …

Experimental approaches directed at addressing these issues are limited by several
considerations. First, the close association between obesity and OSA often obscures …

Obstructive sleep apnoea (OSA) is a common disorder in which repetitive apnoeas expose
the cardiovascular system to cycles of hypoxia, exaggerated negative intrathoracic pressure …