Th1 and Th2 lymphocytes in autoimmune disease
IJ Crane, JV Forrester - Critical Reviews™ in Immunology, 2005 - dl.begellhouse.com
This review reconsiders how the Th1/Th2 paradigm can be applied to Th1-mediated
autoimmune disease. Although there is evidence that autoimmune diseases such as …
autoimmune disease. Although there is evidence that autoimmune diseases such as …
In vivo gene expression revealed by cDNA arrays: the pattern in relapsing–remitting multiple sclerosis patients compared with normal subjects
M Ramanathan, B Weinstock-Guttman… - Journal of …, 2001 - Elsevier
Objectives: To use DNA arrays to identify differences in gene expression associated with
relapsing–remitting (RR) MS. Methods: Total RNA was isolated from monocyte depleted …
relapsing–remitting (RR) MS. Methods: Total RNA was isolated from monocyte depleted …
SWAP-70-like adapter of T cells, an adapter protein that regulates early TCR-initiated signaling in Th2 lineage cells
Y Tanaka, K Bi, R Kitamura, S Hong, Y Altman… - Immunity, 2003 - cell.com
We describe the isolation of a protein, SWAP-70-like adapter of T cells (SLAT), which is
expressed at high levels in thymocytes and differentiated Th2 cells. SLAT expression was …
expressed at high levels in thymocytes and differentiated Th2 cells. SLAT expression was …
Antibodies to myelin basic protein, myelin oligodendrocytes peptides, α‐β‐crystallin, lymphocyte activation and cytokine production in patients with multiple sclerosis
A Vojdani, E Vojdani, E Cooper - Journal of internal medicine, 2003 - Wiley Online Library
Abstract Vojdani A, Vojdani E, Cooper E (Laboratory of Comparative Neuroimmunology,
David Geffen School of Medicine at UCLA, University of California Los Angeles, Los …
David Geffen School of Medicine at UCLA, University of California Los Angeles, Los …
Identification of UNC119 as a novel activator of SRC-type tyrosine kinases
Lyn, an Src-type tyrosine kinase, is associated with the interleukin (IL)-5 receptor in
eosinophils. The mechanism of its activation is unknown. Through yeast two-hybrid …
eosinophils. The mechanism of its activation is unknown. Through yeast two-hybrid …
[HTML][HTML] Mechanism of T cell hyporesponsiveness to HBcAg is associated with regulatory T cells in chronic hepatitis B
Y Kondo, K Kobayashi, Y Ueno, M Shiina… - World journal of …, 2006 - ncbi.nlm.nih.gov
AIM: To study the mechanisms of hyporesponsiveness of HBV-specific CD4+ T cells by
testing TH 1 and TH 2 commitment and regulatory T cells. METHODS: Nine patients with …
testing TH 1 and TH 2 commitment and regulatory T cells. METHODS: Nine patients with …
Weak TCR stimulation induces a calcium signal that triggers IL‐4 synthesis, stronger TCR stimulation induces MAP kinases that control IFN‐γ production
Th1 and Th2 cells produce different cytokines and have distinct functions. Th1/Th2 cell
differentiation is influenced, among other factors, by the nature of TCR‐MHC interactions …
differentiation is influenced, among other factors, by the nature of TCR‐MHC interactions …
Protein kinase C‐mediated calcium entry dependent upon dihydropyridine‐sensitive channels: a T‐cell receptor‐coupled signaling pathway involved in interleukin 4 …
Signaling events induced by T‐cell receptor (TCR) engagement involve a cascade of
tyrosine phosphorylation events leading to activation of several downstream pathways and …
tyrosine phosphorylation events leading to activation of several downstream pathways and …
SWAP‐70‐like adapter of T cells: a novel Lck‐regulated guanine nucleotide exchange factor coordinating actin cytoskeleton reorganization and Ca2+ signaling in T …
S Bécart, A Altman - Immunological reviews, 2009 - Wiley Online Library
SWAP‐70‐like adapter of T cells (SLAT) is a recently identified guanine nucleotide
exchange factor (GEF) for Cdc42 and Rac1, which is highly expressed in both thymocytes …
exchange factor (GEF) for Cdc42 and Rac1, which is highly expressed in both thymocytes …
Characterization of regulatory t-cells in multiple sclerosis patients treated with interferon beta-1a
Background: Regulatory T-Cells (Treg Cells), as one of the immune system components,
have been highly effective in the autoimmune diseases prevention, particularly multiple …
have been highly effective in the autoimmune diseases prevention, particularly multiple …