NADPH oxidases (NOX): an overview from discovery, molecular mechanisms to physiology and pathology

A Vermot, I Petit-Härtlein, SME Smith, F Fieschi - Antioxidants, 2021 - mdpi.com
The reactive oxygen species (ROS)-producing enzyme NADPH oxidase (NOX) was first
identified in the membrane of phagocytic cells. For many years, its only known role was in …

[HTML][HTML] Biochemical basis and metabolic interplay of redox regulation

L Zhang, X Wang, R Cueto, C Effi, Y Zhang, H Tan… - Redox biology, 2019 - Elsevier
Accumulated evidence strongly indicates that oxidative stress, characterized by an
imbalance between reactive oxygen species (ROS) production and antioxidants in favor of …

Reactive oxygen species are regulated by immune deficiency and Toll pathways in determining the host specificity of honeybee gut bacteria

L Guo, J Tang, M Tang, S Luo… - Proceedings of the …, 2023 - National Acad Sciences
Host specificity is observed in gut symbionts of diverse animal lineages. But how hosts
maintain symbionts while rejecting their close relatives remains elusive. We use eusocial …

Mechanisms of oxidative stress in plants: from classical chemistry to cell biology

V Demidchik - Environmental and experimental botany, 2015 - Elsevier
Oxidative stress is a complex chemical and physiological phenomenon that accompanies
virtually all biotic and abiotic stresses in higher plants and develops as a result of …

Where in the world do bacteria experience oxidative stress?

JA Imlay - Environmental microbiology, 2019 - Wiley Online Library
Reactive oxygen species–superoxide, hydrogen peroxide and hydroxyl radicals–have long
been suspected of constraining bacterial growth in important microbial habitats and indeed …

The redox code

DP Jones, H Sies - Antioxidants & redox signaling, 2015 - liebertpub.com
Significance: The redox code is a set of principles that defines the positioning of the
nicotinamide adenine dinucleotide (NAD, NADP) and thiol/disulfide and other redox systems …

Profiling cellular diversity in sponges informs animal cell type and nervous system evolution

JM Musser, KJ Schippers, M Nickel, G Mizzon… - Science, 2021 - science.org
The evolutionary origin of metazoan cell types such as neurons and muscles is not known.
Using whole-body single-cell RNA sequencing in a sponge, an animal without nervous …

The role of phenolic compounds in plant resistance

K Kulbat - Biotechnology and Food Science, 2016 - eczasopisma.p.lodz.pl
Phenolic compounds are plant secondary metabolites playing important roles in plant
resistance. Their chemical structure is based on at least one aromatic ring bonded to one or …

NADPH oxidases, reactive oxygen species, and the kidney: friend and foe

M Sedeek, R Nasrallah, RM Touyz… - Journal of the American …, 2013 - journals.lww.com
Reactive oxygen species (ROS) play an important role in normal cellular physiology. They
regulate different biologic processes such as cell defense, hormone synthesis and signaling …

How microbes defend themselves from incoming hydrogen peroxide

A Sen, JA Imlay - Frontiers in immunology, 2021 - frontiersin.org
Microbes rely upon iron as a cofactor for many enzymes in their central metabolic processes.
The reactive oxygen species (ROS) superoxide and hydrogen peroxide react rapidly with …