Harmonization strategies for multicenter radiomics investigations
Carrying out large multicenter studies is one of the key goals to be achieved towards a faster
transfer of the radiomics approach in the clinical setting. This requires large-scale radiomics …
transfer of the radiomics approach in the clinical setting. This requires large-scale radiomics …
Tackling the widespread and critical impact of batch effects in high-throughput data
High-throughput technologies are widely used, for example to assay genetic variants, gene
and protein expression, and epigenetic modifications. One often overlooked complication …
and protein expression, and epigenetic modifications. One often overlooked complication …
Microbiome analyses of blood and tissues suggest cancer diagnostic approach
Systematic characterization of the cancer microbiome provides a unique opportunity to
develop cancer diagnostics that exploit non-human, microbial-derived molecules in a major …
develop cancer diagnostics that exploit non-human, microbial-derived molecules in a major …
A practical guide to linking brain-wide gene expression and neuroimaging data
The recent availability of comprehensive, brain-wide gene expression atlases such as the
Allen Human Brain Atlas (AHBA) has opened new opportunities for understanding how …
Allen Human Brain Atlas (AHBA) has opened new opportunities for understanding how …
Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration
Genome-wide association studies (GWAS) have identified genetic variants at 34 loci
contributing to age-related macular degeneration (AMD),–. We generated transcriptional …
contributing to age-related macular degeneration (AMD),–. We generated transcriptional …
[HTML][HTML] Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions
L Narunsky-Haziza, GD Sepich-Poore, I Livyatan… - Cell, 2022 - cell.com
Cancer-microbe associations have been explored for centuries, but cancer-associated fungi
have rarely been examined. Here, we comprehensively characterize the cancer mycobiome …
have rarely been examined. Here, we comprehensively characterize the cancer mycobiome …
Removing batch effects in analysis of expression microarray data: an evaluation of six batch adjustment methods
The expression microarray is a frequently used approach to study gene expression on a
genome-wide scale. However, the data produced by the thousands of microarray studies …
genome-wide scale. However, the data produced by the thousands of microarray studies …
Using control genes to correct for unwanted variation in microarray data
JA Gagnon-Bartsch, TP Speed - Biostatistics, 2012 - academic.oup.com
Microarray expression studies suffer from the problem of batch effects and other unwanted
variation. Many methods have been proposed to adjust microarray data to mitigate the …
variation. Many methods have been proposed to adjust microarray data to mitigate the …
Batch effect removal methods for microarray gene expression data integration: a survey
Genomic data integration is a key goal to be achieved towards large-scale genomic data
analysis. This process is very challenging due to the diverse sources of information resulting …
analysis. This process is very challenging due to the diverse sources of information resulting …
Omics-based strategies in precision medicine: toward a paradigm shift in inborn errors of metabolism investigations
The rise of technologies that simultaneously measure thousands of data points represents
the heart of systems biology. These technologies have had a huge impact on the discovery …
the heart of systems biology. These technologies have had a huge impact on the discovery …