Structure, function, and pharmacology of glutamate receptor ion channels
Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …
The glutamate receptor ion channels
The ionotropic glutamate receptors are ligand-gated ion channels that mediate the vast
majority of excitatory neurotransmission in the brain. The cloning of cDNAs encoding …
majority of excitatory neurotransmission in the brain. The cloning of cDNAs encoding …
Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learning
D Zamanillo, R Sprengel, Ø Hvalby, V Jensen… - Science, 1999 - science.org
Gene-targeted mice lacking thel-α-amino-3-hydroxy-5-methylisoxazole-4-propionate
(AMPA) receptor subunit GluR-A exhibited normal development, life expectancy, and fine …
(AMPA) receptor subunit GluR-A exhibited normal development, life expectancy, and fine …
[HTML][HTML] Cell type and pathway dependence of synaptic AMPA receptor number and variability in the hippocampus
It has been suggested that some glutamatergic synapses lack functional AMPA receptors.
We used quantitative immunogold localization to determine the number and variability of …
We used quantitative immunogold localization to determine the number and variability of …
Segregation of different GABAA receptors to synaptic and extrasynaptic membranes of cerebellar granule cells
Two types of GABAA receptor-mediated inhibition (phasic and tonic) have been described in
cerebellar granule cells, although these cells receive GABAergic input only from a single cell …
cerebellar granule cells, although these cells receive GABAergic input only from a single cell …
Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport
M Setou, T Nakagawa, DH Seog, N Hirokawa - Science, 2000 - science.org
Experiments with vesicles containing N-methyl-d-aspartate (NMDA) receptor 2B (NR2B
subunit) show that they are transported along microtubules by KIF17, a neuron-specific …
subunit) show that they are transported along microtubules by KIF17, a neuron-specific …
Phosphorylation of microtubule-associated protein 2 (MAP2) and its relevance for the regulation of the neuronal cytoskeleton function
C Sánchez, J Dıaz-Nido, J Avila - Progress in neurobiology, 2000 - Elsevier
Neurons, the basic information processing units of the nervous system, are characterized by
a complex polar morphology which is essential for their function. To attain their precise …
a complex polar morphology which is essential for their function. To attain their precise …
A developmental change in NMDA receptor-associated proteins at hippocampal synapses
N Sans, RS Petralia, YX Wang, J Blahos… - Journal of …, 2000 - Soc Neuroscience
The membrane-associated guanylate kinases [Chapsyn-110/postsynaptic density-93 (PSD-
93), synapse-associated protein-90 (SAP-90)/PSD-95, and SAP-102] are believed to cluster …
93), synapse-associated protein-90 (SAP-90)/PSD-95, and SAP-102] are believed to cluster …
[HTML][HTML] Genetic analysis of glutamate receptors in Drosophila reveals a retrograde signal regulating presynaptic transmitter release
SA Petersen, RD Fetter, JN Noordermeer… - Neuron, 1997 - cell.com
Postsynaptic sensitivity to glutamate was genetically manipulated at the Drosophila
neuromuscular junction (NMJ) to test whether postsynaptic activity can regulate presynaptic …
neuromuscular junction (NMJ) to test whether postsynaptic activity can regulate presynaptic …
Polarized and compartment-dependent distribution of HCN1 in pyramidal cell dendrites
A Lörincz, T Notomi, G Tamás, R Shigemoto… - Nature …, 2002 - nature.com
An ion channel's function depends largely on its location and density on neurons. Here we
used high-resolution immunolocalization to determine the subcellular distribution of the …
used high-resolution immunolocalization to determine the subcellular distribution of the …