Liquid chromatography (LC) based techniques in combination with mass spectrometry (MS)
detection have had a large impact on the development of new pharmaceuticals in the past …

Traditional Chinese medicine (TCM) has been an indispensable source of drugs for curing
various human diseases. However, the inherent chemical diversity and complexity of TCM …

During the last decade, forensic toxicologists have evidenced an exponential increase in the
number of new psychoactive substances (NPS) that are available on the drug market …

The term 'opioids' refers to both the natural compounds ('opiates') which are extracted from
the opium poppy plant (Papaver somniferum) and their semi-synthetic and synthetic …

Mass spectrometry has been the “gold standard” for drugs of abuse (DoA) analysis for many
decades because of the selectivity and sensitivity it affords. Recent progress in all aspects of …

This trend article reviews papers with hyphenated high-resolution mass spectrometry
(HRMS) approaches applied in analytical toxicology, particularly in clinical and forensic …

Detection of new psychoactive substances and synthetic opioids is generally performed by
means of targeted methods in mass spectrometry, as they generally provide adequate …

Purpose Since the 1980s, the detection sensitivity of mass spectrometers has increased by
improving the analysis of drugs in hair. Accordingly, the number of hair strands required for …

Substandard/counterfeit drugs are a growing global problem. According to the World Health
Organisation, counterfeit medicines are medicines that are mislabelled deliberately and …

The misuse of psychoactive substances is attracting a great deal of attention from the
general public. An increase use of psychoactive substances is observed among young …