Colorectal cancer (CRC) is one of the most commonly diagnosed cancers and poses a
major burden on the human health worldwide. At the moment, treatment of CRC consists of …

The fact that the Mediterranean diet could represent a source of natural compounds with
cancer-preventive and therapeutic activity has been the object of great interest, especially …

Persistently high, worldwide mortality from cancer highlights the unresolved challenges of
disease surveillance and detection that impact survival. Development of a non-invasive …

Despite the discovery of numerous driving and passenger genes that play key roles in
cancer characteristics, progress in cancer treatment has not been satisfactory. This is mainly …

Colorectal cancer (CRC) is the third most prevalent cancer worldwide. Current studies have
demonstrated that tumor-derived extracellular vesicles (EVs) from different cancer cell types …

Small interfering RNA (siRNA) holds promise as a therapeutic approach for various
diseases, yet challenges persist in achieving efficient delivery, biodistribution, and …

Colon cancer, one of the most common and fatal cancers worldwide, is characterized by
stepwise accumulation of specific genetic alterations in tumor suppressor genes or …

Considerable progress has recently been made in cancer immunotherapy, including
immune checkpoint blockade, cancer vaccine, and adoptive T cell methods. The lack of …

Simple Summary Colorectal cancer (CRC) has become one of the leading causes of cancer-
related morbidity and mortality worldwide. Immune checkpoint inhibitors (ICIs) and adoptive …

FOLFOXIRI chemotherapy is a first-line therapy for advanced or metastatic colorectal cancer
(CRC), yet its therapeutic efficacy remains limited. Immunostimulatory therapies like …