[HTML][HTML] Nicotine on the developing brain

EM Castro, S Lotfipour, FM Leslie - Pharmacological research, 2023 - Elsevier
Developmental periods such as gestation and adolescence have enhanced plasticity
leaving the brain vulnerable to harmful effects from nicotine use. Proper brain maturation …

[HTML][HTML] Epigenetic mechanisms of nicotine dependence

C Muenstermann, KJ Clemens - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
Smoking continues to be a leading cause of preventable disease and death worldwide.
Nicotine dependence generates a lifelong propensity towards cravings and relapse …

Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits

NYA Sey, B Hu, M Iskhakova, S Lee, H Sun… - Molecular …, 2022 - nature.com
Cigarette smoking and alcohol use are among the most prevalent substances used
worldwide and account for a substantial proportion of preventable morbidity and mortality …

MicroRNAs in drug addiction: Current status and future perspectives

Y Zhao, F Qin, S Han, S Li, Y Zhao, H Wang… - Pharmacology & …, 2022 - Elsevier
Drug addiction is a chronic and relapsing brain disorder characterized by compulsive drug
seeking and continued drug use despite adverse consequences. The high prevalence and …

Adipose tissue exosome circ_sxc mediates the modulatory of Adiposomes on brain aging by inhibiting brain dme-miR-87-3p

Q Li, L Wang, C Tang, X Wang, Z Yu, X Ping… - Molecular …, 2024 - Springer
Aging of the brain usually leads to the decline of neurological processes and is a major risk
factor for various neurodegenerative diseases, including sleep disturbances and cognitive …

Precision behavioral management (PBM) and cognitive control as a potential therapeutic and prophylactic modality for reward deficiency syndrome (RDS): is there …

MA Madigan, A Gupta, A Bowirrat, D Baron… - International Journal of …, 2022 - mdpi.com
This brief commentary aims to provide an overview of the available and relatively new
precision management of reward deficiencies manifested as substance and behavioral …

Early life exposure to nicotine: postnatal metabolic, neurobehavioral and respiratory outcomes and the development of childhood cancers

L Jamshed, GA Perono, S Jamshed… - Toxicological …, 2020 - academic.oup.com
Cigarette smoking during pregnancy is associated with numerous obstetrical, fetal, and
developmental complications, as well as an increased risk of adverse health consequences …

Non-coding RNA in alcohol use disorder by affecting synaptic plasticity

S Zhu, J Wu, J Hu - Experimental brain research, 2022 - Springer
Alcohol use disorder (AUD) is one of the most serious public health problems worldwide.
AUD is a complex disorder, and there is ample evidence that genetic predisposition is …

[HTML][HTML] Substance-induced psychiatric disorders, epigenetic and microbiome alterations, and potential for therapeutic interventions

S Nohesara, H Mostafavi Abdolmaleky… - Brain Sciences, 2024 - mdpi.com
Substance use disorders (SUDs) are complex biopsychosocial diseases that cause
neurocognitive deficits and neurological impairments by altering the gene expression in …

The role of miRNAs as new molecular biomarkers for dating the age of wound production: a systematic review

S De Simone, E Giacani, MA Bosco, S Vittorio… - Frontiers in …, 2022 - frontiersin.org
Background: The timing of wounds production is a significant issue in forensic pathology.
Although various methods have been evaluated, obtaining an accurate dating of lesions is …