Cellular origin of Kaposi's sarcoma and Kaposi's sarcoma-associated herpesvirus-induced cell reprogramming

L Cancian, A Hansen, C Boshoff - Trends in cell biology, 2013 - cell.com
Kaposi's sarcoma (KS) is the most common malignancy in untreated HIV patients. KS is
characterised by abnormal neoangiogenesis, inflammation, and proliferation of tumour cells …

Cancer “causation” by infections—individual contributions and synergistic networks

H Zur Hausen, EM de Villiers - Seminars in oncology, 2014 - Elsevier
The search for infectious agents playing a role in human carcinogenesis and their
identification remain important issues. This could provide clues for a broader spectrum of …

Gene expression in meningeal lymphatic endothelial cells following traumatic brain injury in mice

R Shimada, Y Tatara, K Kibayashi - PLoS One, 2022 - journals.plos.org
Meningeal lymphatic vessels transport both the cerebrospinal fluid and interstitial fluid to the
deep cervical lymph nodes. Traumatic brain injury (TBI) is accompanied by meningeal …

Decidual lymphatic endothelial cell‐derived granulocyte‐macrophage colony‐stimulating factor induces M1 macrophage polarization via the NF‐κB pathway in …

YJ Jung, Y Lee, H Kwon, HP Kim… - American Journal of …, 2023 - Wiley Online Library
Problem Direct interactions between macrophages and lymphatic vessels have been shown
previously. In pre‐eclampsia (PE), macrophages are dominantly polarized into a …

ERK-dependent downregulation of the atypical chemokine receptor D6 drives tumor aggressiveness in Kaposi sarcoma

B Savino, N Caronni, A Anselmo, F Pasqualini… - Cancer immunology …, 2014 - AACR
D6 is an atypical chemokine receptor acting as a decoy and scavenger for inflammatory CC
chemokines expressed in lymphatic endothelial cells. Here, we report that D6 is expressed …

Aberrant activation of Notch signaling inhibits PROX1 activity to enhance the malignant behavior of thyroid cancer cells

D Choi, S Ramu, E Park, E Jung, S Yang, W Jung… - Cancer research, 2016 - AACR
Papillary thyroid cancer (PTC) is one of the most common endocrine malignancies
associated with significant morbidity and mortality. Although multiple studies have …

Essential role of Apelin signaling during lymphatic development in zebrafish

JD Kim, Y Kang, J Kim, I Papangeli… - … , and vascular biology, 2014 - Am Heart Assoc
Objective—Apelin and its cognate receptor Aplnr/Apj are essential for diverse biological
processes. However, the function of Apelin signaling in lymphatic development remains to …

Site-specific association with host and viral chromatin by Kaposi's sarcoma-associated herpesvirus LANA and its reversal during lytic reactivation

A Mercier, C Arias, AS Madrid, MM Holdorf… - Journal of …, 2014 - Am Soc Microbiol
Latency-associated nuclear antigen (LANA), a multifunctional protein expressed by the
Kaposi sarcoma-associated herpesvirus (KSHV) in latently infected cells, is required for …

Deregulation of HDAC5 by viral interferon regulatory factor 3 plays an essential role in Kaposi's sarcoma-associated herpesvirus-induced lymphangiogenesis

HR Lee, F Li, UY Choi, HR Yu, GM Aldrovandi, P Feng… - MBio, 2018 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent for Kaposi's
sarcoma (KS), which is one of the most common HIV-associated neoplasms. The …

[HTML][HTML] Development of a radiosensitivity gene signature for patients with soft tissue sarcoma

Z Tang, Q Zeng, Y Li, X Zhang, J Ma, MJ Suto, B Xu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Adjuvant radiotherapy is an important clinical treatment option for the majority of sarcomas.
The motivation of current study is to identify a gene signature and to predict radiosensitive …