Interpreting the widespread nonlinear force spectra of intermolecular bonds

RW Friddle, A Noy, JJ De Yoreo - Proceedings of the …, 2012 - National Acad Sciences
Single molecule force spectroscopy probes the strength, lifetime, and energetic details of
intermolecular interactions in a simple experiment. A growing number of these studies have …

Single-molecule scale quantification reveals interactions underlying protein–protein interface: from forces to non-covalent bonds

H Sun, Y Tian, Y Fu, Y Lei, Y Wang, X Yan… - Physical Chemistry …, 2023 - pubs.rsc.org
Protein–protein interactions (PPIs) between the B-cell lymphoma 2 (Bcl-2) family are
considered a major driving force in cell cycle regulation and signaling. However, how this …

Nanoscale Young's modulus and surface morphology in photocurable polyacrylate/nanosilica composites

H Gojzewski, M Sadej, E Andrzejewska… - European polymer …, 2017 - Elsevier
We studied quantitatively nanomechanical properties (Young's modulus, adhesion force)
and surface morphology of two types of model polymer-nanosilica composites. High …

An ultra-low frictional interface combining FDTS SAMs with molybdenum disulfide

X Gan, Y Peng, Y Wang, X Zeng, H Lang, J Deng… - Nanoscale, 2018 - pubs.rsc.org
Interfacial friction is of crucial importance to ensure the friction-reducing and anti-wear
properties of mechanical microstructures in micro/nanoelectromechanical systems …

Influence of humidity on the nanoadhesion between a hydrophobic and a hydrophilic surface

A Ptak, H Gojzewski, M Kappl, HJ Butt - Chemical Physics Letters, 2011 - Elsevier
The adhesion force between a silicon nitride tip and a 1-dodecanethiol monolayer have
been measured at different loading rates and different humidity. A way to extract the kinetic …

Unbinding kinetics of syndecans by single-molecule force spectroscopy

K Herman, M Lekka, A Ptak - The Journal of Physical Chemistry …, 2018 - ACS Publications
Syndecans are transmembrane proteoglycans that, together with integrins, control cell
interactions with extracellular matrix components. Despite structural similarities between all …

Crucial roles of bond rebinding in rupture behaviors of single molecular bond at ultralow loading rates

D Li, B Ji - International Journal of Applied Mechanics, 2015 - World Scientific
Single-molecule dynamic force spectroscopy (DFS) is a powerful tool for studying
mechanical forces of molecular interactions. Recently, the important role of bond rebinding …

How strong are hydrogen bonds in the peptide model?

J Dąbrowski, W Nowak, A Ptak - Physical Chemistry Chemical Physics, 2020 - pubs.rsc.org
Detailed knowledge of intramolecular hydrogen bonds, including their nanomechanics, in a
peptide secondary structure is crucial for understanding mechanisms of numerous …

How complex is the concanavalin A–carboxypeptidase Y interaction?

K Herman, M Weiss, M Lekka, A Ptak - ACS Chemical Biology, 2019 - ACS Publications
Lectin–carbohydrate interactions can be exploited in ultrasensitive biochemical recognition
or medical diagnosis. For this purpose, besides the high specificity of the interactions, an …

Single-molecule force spectroscopy reveals structural differences of heparan sulfate chains during binding to vitronectin

K Herman, J Zemła, A Ptak, M Lekka - Physical Review E, 2021 - APS
The syndecans represent an ongoing research field focused on their regulatory roles in
normal and pathological conditions. The role of syndecans in cancer progression is well …