Cannabidiol: State of the art and new challenges for therapeutic applications
Over the past years, several lines of evidence support a therapeutic potential of Cannabis
derivatives and in particular phytocannabinoids. Δ 9-THC and cannabidiol (CBD) are the …
derivatives and in particular phytocannabinoids. Δ 9-THC and cannabidiol (CBD) are the …
Cardiovascular effects of marijuana and synthetic cannabinoids: the good, the bad, and the ugly
Dysregulation of the endogenous lipid mediators endocannabinoids and their G-protein-
coupled cannabinoid receptors 1 and 2 (CB1R and CB2R) has been implicated in a variety …
coupled cannabinoid receptors 1 and 2 (CB1R and CB2R) has been implicated in a variety …
Medicinal properties of cannabinoids, terpenes, and flavonoids in cannabis, and benefits in migraine, headache, and pain: an update on current evidence and …
EP Baron - Headache: The Journal of Head and Face Pain, 2018 - Wiley Online Library
Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …
Cannabidiol (CBD) and its analogs: a review of their effects on inflammation
S Burstein - Bioorganic & medicinal chemistry, 2015 - Elsevier
First isolated from Cannabis in 1940 by Roger Adams, the structure of CBD was not
completely elucidated until 1963. Subsequent studies resulted in the pronouncement that …
completely elucidated until 1963. Subsequent studies resulted in the pronouncement that …
[HTML][HTML] Cannabinoids and epilepsy
Cannabis has been used for centuries to treat seizures. Recent anecdotal reports,
accumulating animal model data, and mechanistic insights have raised interest in cannabis …
accumulating animal model data, and mechanistic insights have raised interest in cannabis …
The effects of cannabidiol, a non-intoxicating compound of cannabis, on the cardiovascular system in health and disease
A Kicman, M Toczek - International journal of molecular sciences, 2020 - mdpi.com
Cannabidiol (CBD) is a non-intoxicating and generally well-tolerated constituent of cannabis
which exhibits potential beneficial properties in a wide range of diseases, including …
which exhibits potential beneficial properties in a wide range of diseases, including …
Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress
GW Booz - Free Radical Biology and Medicine, 2011 - Elsevier
Oxidative stress with reactive oxygen species generation is a key weapon in the arsenal of
the immune system for fighting invading pathogens and initiating tissue repair. If excessive …
the immune system for fighting invading pathogens and initiating tissue repair. If excessive …
Cannabidiol reduces neuroinflammation and promotes neuroplasticity and functional recovery after brain ischemia
This study investigated the effects of cannabidiol (CBD), a non-psychotomimetic
phytochemical present in Cannabis sativa, on the cognitive and emotional impairments …
phytochemical present in Cannabis sativa, on the cognitive and emotional impairments …
Cannabidiol and sports performance: a narrative review of relevant evidence and recommendations for future research
Cannabidiol (CBD) is a non-intoxicating cannabinoid derived from Cannabis sativa. CBD
initially drew scientific interest due to its anticonvulsant properties but increasing evidence of …
initially drew scientific interest due to its anticonvulsant properties but increasing evidence of …
Cannabidiol reduces brain damage and improves functional recovery in a neonatal rat model of arterial ischemic stroke
M Ceprián, L Jiménez-Sánchez, C Vargas, L Barata… - …, 2017 - Elsevier
Background and purpose: Currently there is no effective treatment for neonatal arterial
ischemic stroke (AIS). Cannabidiol (CBD) is neuroprotective in models of newborn hypoxic …
ischemic stroke (AIS). Cannabidiol (CBD) is neuroprotective in models of newborn hypoxic …