Dental pulp stem cells: advances to applications

TW Tsutsui - Stem cells and cloning: advances and applications, 2020 - Taylor & Francis
Dental pulp stem cells (DPSCs) have a high capacity for differentiation and the ability to
regenerate a dentin/pulp-like complex. Numerous studies have provided evidence of …

Mesenchymal stem cells derived from dental pulp: a review

E Ledesma-Martínez, VM Mendoza-Núñez… - Stem cells …, 2016 - Wiley Online Library
The mesenchymal stem cells of dental pulp (DPSCs) were isolated and characterized for the
first time more than a decade ago as highly clonogenic cells that were able to generate …

Bone marrow-derived mesenchymal stem cells-derived exosomes promote survival of retinal ganglion cells through miRNA-dependent mechanisms

B Mead, S Tomarev - Stem cells translational medicine, 2017 - academic.oup.com
The loss of retinal ganglion cells (RGC) and their axons is one of the leading causes of
blindness and includes traumatic (optic neuropathy) and degenerative (glaucoma) eye …

Dental pulp stem cells: function, isolation and applications in regenerative medicine

M Tatullo, M Marrelli, KM Shakesheff… - Journal of tissue …, 2015 - Wiley Online Library
Dental pulp stem cells (DPSCs) are a promising source of cells for numerous and varied
regenerative medicine applications. Their natural function in the production of odontoblasts …

Therapeutic potential of dental stem cells

EP Chalisserry, SY Nam, SH Park… - Journal of tissue …, 2017 - journals.sagepub.com
Stem cell biology has become an important field in regenerative medicine and tissue
engineering therapy since the discovery and characterization of mesenchymal stem cells …

[HTML][HTML] Stem cell treatment of degenerative eye disease

B Mead, M Berry, A Logan, RAH Scott, W Leadbeater… - Stem cell …, 2015 - Elsevier
Stem cell therapies are being explored extensively as treatments for degenerative eye
disease, either for replacing lost neurons, restoring neural circuits or, based on more recent …

Paracrine-mediated neuroprotection and neuritogenesis of axotomised retinal ganglion cells by human dental pulp stem cells: comparison with human bone marrow …

B Mead, A Logan, M Berry, W Leadbeater… - PloS one, 2014 - journals.plos.org
We have investigated and compared the neurotrophic activity of human dental pulp stem
cells (hDPSC), human bone marrow-derived mesenchymal stem cells (hBMSC) and human …

Potential roles of dental pulp stem cells in neural regeneration and repair

L Luo, Y He, X Wang, B Key, BH Lee… - Stem cells …, 2018 - Wiley Online Library
This review summarizes current advances in dental pulp stem cells (DPSCs) and their
potential applications in the nervous diseases. Injured adult mammalian nervous system has …

Progress in the use of dental pulp stem cells in regenerative medicine

E Anitua, M Troya, M Zalduendo - Cytotherapy, 2018 - Elsevier
The field of tissue engineering is emerging as a multidisciplinary area with promising
potential for regenerating new tissues and organs. This approach requires the involvement …

Extracellular vesicle therapy for retinal diseases

B Mead, S Tomarev - Progress in retinal and eye research, 2020 - Elsevier
Extracellular vesicles (EV), which include exosomes and microvesicles, are secreted from
virtually every cell. EV contain mRNA, miRNA, lipids and proteins and can deliver this …