SARS-CoV-2, the causative agent of COVID-19, remains among the main causes of global
mortality. Although antigen/antibody-based immunoassays and neutralizing antibodies …

Viral infections can cause serious diseases for humans and animals. Accurate and early
detection of viruses is often crucial for clinical diagnosis and therapy. Aptamers are mostly …

Nucleic acid aptamers are generated by an in vitro molecular evolution method known as
systematic evolution of ligands by exponential enrichment (SELEX). Various candidates are …

Infectious diseases are a serious global problem, which not only take an enormous human
toll but also incur tremendous economic losses. In combating infectious diseases, rapid and …

Today, the treatment of bacterial infections is a major challenge, due to growing rate of
multidrug-resistant bacteria, complication of treatment and increased healthcare costs …

There has clearly been a deluge of international press coverage of the recent outbreak of
Ebolavirus in Africa and is partly related to the “fear factor” that comes across when one is …

Background SELEX technique is employed to select aptamers against wide range of targets.
The in vitro method of aptamer selection using live cells as the target is referred as cell …

Viruses are pathogenic microorganisms that can inhabit and replicate in human bodies
causing a number of widespread infectious diseases such as influenza, gastroenteritis …

Ebola virus (EBOV), member of genus Ebolavirus, family Filoviridae, have a non-segmented,
single-stranded RNA that contains seven genes:(a) nucleoprotein (NP),(b) viral protein 35 …

Despite the great promise of nucleic acid aptamers in the areas of diagnostics and
therapeutics for their facile in vitro development, lack of immunogenicity and other desirable …