K O'Brien, Y Wang - Annual Review of Nutrition, 2023 - annualreviews.org
The placenta is the gatekeeper between the mother and the fetus. Over the first trimester of pregnancy, the fetus is nourished by uterine gland secretions in a process known as …
V Sangkhae, AL Fisher, T Ganz… - Annual Review of …, 2023 - annualreviews.org
Pregnancy entails a large negative balance of iron, an essential micronutrient. During pregnancy, iron requirements increase substantially to support both maternal red blood cell …
Y Zhang, Y Lu, L Jin - International Journal of Molecular Sciences, 2022 - mdpi.com
Iron is a vital element in nearly every living organism. During pregnancy, optimal iron concentration is essential for both maternal health and fetal development. As the barrier …
V Sangkhae, E Nemeth - Free Radical Biology and Medicine, 2019 - Elsevier
As the interface between the fetal and maternal circulation, the placenta facilitates both nutrient and waste exchange for the developing fetus. Iron is essential for healthy …
S Wang, X He, Q Wu, L Jiang, L Chen, Y Yu… - …, 2019 - pmc.ncbi.nlm.nih.gov
Transferrin receptor 1 (Tfr1) mediates the endocytosis of diferric transferrin in order to transport iron, and Tfr1 has been suggested to play an important role in hematopoiesis. To …
J Zaugg, F Solenthaler, C Albrecht - Biochemical pharmacology, 2022 - Elsevier
A successful pregnancy and the birth of a healthy baby depend to a great extent on the controlled supply of essential nutrients via the placenta. Iron is essential for mitochondrial …
The human placenta is a highly specialized organ that is responsible for housing, protecting, and nourishing the fetus across gestation. The placenta is essential as it functions among …
K Kot, D Kosik-Bogacka… - International Journal of …, 2019 - mdpi.com
The aim of the study was to investigate relationships between the concentrations of macroelements (Ca), microelements (Cr, Cu, Fe, Mn, Mo, Ni, Sn, Sr, V, Zn) and heavy metals …
Iron is an essential mineral that participates in oxygen transport, DNA synthesis and repair, and as a cofactor for various cellular processes. Iron deficiency is the most common …