[HTML][HTML] Iron homeostasis during pregnancy

AL Fisher, E Nemeth - The American journal of clinical nutrition, 2017 - Elsevier
During pregnancy, iron needs to increase substantially to support fetoplacental development
and maternal adaptation to pregnancy. To meet these iron requirements, both dietary iron …

The placenta: a maternofetal interface

K O'Brien, Y Wang - Annual Review of Nutrition, 2023 - annualreviews.org
The placenta is the gatekeeper between the mother and the fetus. Over the first trimester of
pregnancy, the fetus is nourished by uterine gland secretions in a process known as …

Iron homeostasis during pregnancy: maternal, placental, and fetal regulatory mechanisms

V Sangkhae, AL Fisher, T Ganz… - Annual Review of …, 2023 - annualreviews.org
Pregnancy entails a large negative balance of iron, an essential micronutrient. During
pregnancy, iron requirements increase substantially to support both maternal red blood cell …

Iron metabolism and ferroptosis in physiological and pathological pregnancy

Y Zhang, Y Lu, L Jin - International Journal of Molecular Sciences, 2022 - mdpi.com
Iron is a vital element in nearly every living organism. During pregnancy, optimal iron
concentration is essential for both maternal health and fetal development. As the barrier …

Placental iron transport: The mechanism and regulatory circuits

V Sangkhae, E Nemeth - Free Radical Biology and Medicine, 2019 - Elsevier
As the interface between the fetal and maternal circulation, the placenta facilitates both
nutrient and waste exchange for the developing fetus. Iron is essential for healthy …

Transferrin receptor 1-mediated iron uptake plays an essential role in hematopoiesis

S Wang, X He, Q Wu, L Jiang, L Chen, Y Yu… - …, 2019 - pmc.ncbi.nlm.nih.gov
Transferrin receptor 1 (Tfr1) mediates the endocytosis of diferric transferrin in order to
transport iron, and Tfr1 has been suggested to play an important role in hematopoiesis. To …

[HTML][HTML] Materno-fetal iron transfer and the emerging role of ferroptosis pathways

J Zaugg, F Solenthaler, C Albrecht - Biochemical pharmacology, 2022 - Elsevier
A successful pregnancy and the birth of a healthy baby depend to a great extent on the
controlled supply of essential nutrients via the placenta. Iron is essential for mitochondrial …

Maternal, fetal and placental regulation of placental iron trafficking

KO O'Brien - Placenta, 2022 - Elsevier
The human placenta is a highly specialized organ that is responsible for housing, protecting,
and nourishing the fetus across gestation. The placenta is essential as it functions among …

Interactions between 14 elements in the human placenta, fetal membrane and umbilical cord

K Kot, D Kosik-Bogacka… - International Journal of …, 2019 - mdpi.com
The aim of the study was to investigate relationships between the concentrations of
macroelements (Ca), microelements (Cr, Cu, Fe, Mn, Mo, Ni, Sn, Sr, V, Zn) and heavy metals …

Maternal iron homeostasis: effect on placental development and function

H Roberts, SL Bourque, SJ Renaud - Reproduction, 2020 - rep.bioscientifica.com
Iron is an essential mineral that participates in oxygen transport, DNA synthesis and repair,
and as a cofactor for various cellular processes. Iron deficiency is the most common …