The so-called 'replicability crisis' has sparked methodological discussions in many areas of
science in general, and in psychology in particular. This has led to recent endeavours to …

Anxiety disorders are the most common mental disorders and are often chronic and
disabling. Although exposure-based treatments are effective, a substantial number of …

Why do only some individuals develop pathological anxiety following adverse events? Fear
acquisition, extinction and return of fear paradigms serve as experimental learning models …

Translational neuroscience bridges insights from specific mechanisms in rodents to complex
functions in humans and is key to advance our general understanding of central nervous …

Background Comorbidity of anxiety disorders, stressor-and trauma-related disorders, and
substance use disorders is extremely common. Moreover, therapies that reduce pathological …

The formation and persistence of negative pain-related expectations by classical
conditioning remain incompletely understood. We elucidated behavioural and neural …

Here, we follow the call to target measurement reliability as a key prerequisite for individual-
level predictions in translational neuroscience by investigating (1) longitudinal reliability at …

Adverse childhood experiences (ACEs) are a major risk factor for the development of
multiple psychopathological conditions, but the mechanisms underlying this link are poorly …

Negative emotionality is a well-established and stable risk factor for affective disorders.
Individual differences in negative emotionality have been linked to associative learning …

Exposure to adverse experiences is a well‐established major risk factor for affective
psychopathology. The vulnerability of deleterious sequelae is assumed in maladaptive …