Viral infections are one of the leading causes of human illness. Viruses take over host cell
signaling cascades for their replication and infection. Calcium (Ca 2+) is a versatile and …

Extensive work has characterized endoplasmic reticulum (ER) and mitochondrial stress
responses. In contrast, very little has been published about stress responses in lysosomes; …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is an enveloped, single-
stranded RNA virus. Humans infected with SARS-CoV-2 develop a disease known as …

Resistance to the anti-cancer effects of chemotherapeutic agents (chemoresistance) is a
major issue for people living with cancer and their providers. A diverse set of cellular and …

Ion channels play key roles in almost all facets of cellular physiology and have emerged as
key host cell factors for a multitude of viral infections. A catalogue of ion channel-blocking …

HIV‐1 Tat is essential for HIV‐1 replication and appears to play an important role in the
pathogenesis of HIV‐associated neurological complications. Secreted from infected or …

Chloroquine (CQ) and its analogue hydroxychloroquine (HCQ) have been thrust into our
everyday vernacular because some believe, based on very limited basic and clinical data …

Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) is the virus that causes
coronavirus disease 2019 (COVID-19); a worldwide pandemic as declared by the World …

The outbreak of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) has led to
coronavirus disease-19 (COVID-19); a pandemic disease that has resulted in devastating …

Lysosomes offer a unique arrangement of degradative, exocytic, and signaling capabilities
that make their continued function critical to cellular homeostasis. Lysosomes owe their …