Intrathecal drug delivery in the era of nanomedicine

MJ Fowler, JD Cotter, BE Knight… - Advanced drug delivery …, 2020 - Elsevier
Administration of substances directly into the cerebrospinal fluid (CSF) that surrounds the
brain and spinal cord is one approach that can circumvent the blood-brain barrier to enable …

A critical review of white matter changes in Huntington's disease

C Casella, I Lipp, A Rosser, DK Jones… - Movement …, 2020 - Wiley Online Library
Huntington's disease is a genetic neurodegenerative disorder. White matter alterations have
recently been identified as a relevant pathophysiological feature of Huntington's disease, but …

Translational approaches for brain delivery of biologics via cerebrospinal fluid

SS Sadekar, M Bowen, H Cai… - Clinical …, 2022 - Wiley Online Library
Delivery of biologics via cerebrospinal fluid (CSF) has demonstrated potential to access the
tissues of the central nervous system (CNS) by circumventing the blood‐brain barrier and …

Recent studies on berry bioactives and their health-promoting roles

B Vahapoglu, E Erskine, B Gultekin Subasi… - Molecules, 2021 - mdpi.com
Along with the increased knowledge about the positive health effects of food bioactives, the
eating habits of many individuals have changed to obtain higher nutritional benefits from …

Autonomic dysfunction in Parkinson disease and animal models

JM Metzger, ME Emborg - Clinical Autonomic Research, 2019 - Springer
Parkinson disease has traditionally been classified as a movement disorder, despite
patients' accounts of diverse symptoms stemming from impairments in numerous body …

The squirrel monkey model in clinical neuroscience

J Royo, SJ Forkel, P Pouget, MT de Schotten - … & Biobehavioral Reviews, 2021 - Elsevier
Clinical neuroscience research relying on animal models brought valuable translational
insights into the function and pathologies of the human brain. The anatomical, physiological …

Fluorine‐18 fluorodeoxyglucose positron emission tomography imaging exhibits increased SUVmax at the level of the spinal intumescence in normal dogs

JM French, A Brody, D von Stade… - Veterinary Radiology …, 2020 - Wiley Online Library
Positron emission tomography (PET) imaging utilizing fluorine‐18 labeled
fluorodeoxyglucose is a relatively new imaging modality in veterinary medicine that is …

High resolution micro-CT imaging in mice stroke models: from 3D detailed infarct characterization to automatic area segmentation

R Pinto, J Matula, M Gomez-Lazaro, M Sousa… - bioRxiv, 2022 - biorxiv.org
Characterization of brain infarct lesion in rodent models of stroke is crucial to assess the
outcome of stroke therapies and to study the disease pathophysiology. However, so far it …

Investigation of mechanical threshold to concussion

S Premi - 2019 - theses.hal.science
Concussion, in spite of being a mild traumatic brain injury, involves serious long term
consequences and can adversely affect the life of an individual, their family and the society …

[PDF][PDF] Identifying Behavioral Movements of a Mouse Using Machine Learning

S Mantripragada, E Dionne, J Chen - Columbia Junior Science …, 2020 - cjsjournal.org
In developmental neuroscience, there is a need to understand how state plays an active role
in the developing brain. This paper presents a novel approach of using machine learning …