DNA methylation-based testing in liquid biopsies as detection and prognostic biomarkers for the four major cancer types

V Constâncio, SP Nunes, R Henrique, C Jerónimo - Cells, 2020 - mdpi.com
Lung, breast, colorectal, and prostate cancers are the most incident worldwide. Optimal
population-based cancer screening methods remain an unmet need, since cancer detection …

Methylation of cell-free circulating DNA in the diagnosis of cancer

K Warton, G Samimi - Frontiers in molecular biosciences, 2015 - frontiersin.org
A range of molecular alterations found in tumor cells, such as DNA mutations and DNA
methylation, is reflected in cell-free circulating DNA (circDNA) released from the tumor into …

[HTML][HTML] Reducing anastomotic leak in colorectal surgery: The old dogmas and the new challenges

J Meyer, S Naiken, N Christou, E Liot… - World journal of …, 2019 - ncbi.nlm.nih.gov
Anastomotic leak (AL) constitutes a significant issue in colorectal surgery, and its incidence
has remained stable over the last years. The use of intra-abdominal drain or the use of …

LncRNAs with miRNAs in regulation of gastric, liver, and colorectal cancers: updates in recent years

C Tam, JH Wong, SKW Tsui, T Zuo, TF Chan… - Applied microbiology and …, 2019 - Springer
Long noncoding RNA (lncRNA) is a kind of RNAi molecule composed of hundreds to
thousands of nucleotides. There are several major types of functional lncRNAs which …

[HTML][HTML] Diagnostic and prognostic potential of tissue and circulating long non-coding RNAs in colorectal tumors

O Galamb, BK Barták, A Kalmár, ZB Nagy… - World journal of …, 2019 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) are members of the non-protein coding RNA family
longer than 200 nucleotides. They participate in the regulation of gene and protein …

The Quaking RNA‐binding proteins as regulators of cell differentiation

DP Neumann, GJ Goodall… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
The RNA‐binding protein Quaking (QKI) has emerged as a potent regulator of cellular
differentiation in developmental and pathological processes. The QKI gene is itself …

Noncoding RNAs in the development, diagnosis, and prognosis of colorectal cancer

M Weng, D Wu, C Yang, H Peng, G Wang, T Wang… - Translational …, 2017 - Elsevier
More than 90% of the human genome is actively transcribed, but less than 2% of the total
genome encodes protein-coding RNA, and thus, noncoding RNA (ncRNA) is a major …

Mechanisms of long non‐coding RNA function in colorectal cancer tumorigenesis

A Poursheikhani, MR Abbaszadegan… - Asia‐Pacific Journal …, 2021 - Wiley Online Library
Colorectal cancer (CRC) is one of the most common cancers globally. Although a variety of
CRC screening methods have been developed, many patients are diagnosed at advanced …

[HTML][HTML] Long non-coding RNAs in colorectal cancer: progression and future directions

Y Yang, P Junjie, C Sanjun, Y Ma - Journal of Cancer, 2017 - ncbi.nlm.nih.gov
Identification of the colorectal adenoma-carcinoma sequence with its corresponding genetic
and epigenetic alterations has significantly increased our knowledge of the …

[图书][B] Non-coding RNAs as biomarkers for colorectal cancer screening and early detection

O Slaby - 2016 - Springer
Early detection of colorectal cancer (CRC) is the key for prevention and the ability to impact
long-term survival of CRC patients. Current CRC screening modalities are inadequate for …