The kidneys play a key role in maintaining total body homeostasis. The complexity of this
task is reflected in the unique architecture of the organ. Ureteral obstruction greatly affects …

The use of total volatile basic nitrogen (TVB‐N) as a quality parameter for fish is rapidly
growing to include other types of meat. Investigations of meat quality have recently focused …

Heightened effector function and prolonged persistence, the key attributes of Th1 and Th17
cells, respectively, are key features of potent anti-tumor T cells. Here, we established ex vivo …

A key and highly regulated enzyme that is required for the biosynthesis of monounsaturated
fatty acids is stearoyl-CoA desaturase (SCD), which catalyzes the D9-cis desaturation of a …

Metabolic flexibility describes the ability of cells to respond or adapt its metabolism to
support and enable rapid proliferation, continuous growth, and survival in hostile conditions …

Carnitine acyltransferases catalyze the reversible transfer of acyl groups from acyl‐
coenzyme A esters to l‐carnitine, forming acyl‐carnitine esters that may be transported …

Significance: The p53 tumor suppressor has been dubbed the “guardian of genome”
because of its various roles in the response to DNA damage such as DNA damage repair …

Aging is associated with dysregulation of glucose and lipid metabolism. Various factors that
contribute to the dysregulation include both modifiable (eg obesity, insulin resistance) and …

The incidence of diabetes is increasing globally, with cardiovascular disease accounting for
a substantial number of diabetes-related deaths. Although atherosclerotic vascular disease …

Membrane-bound O-acyltransferases (MBOATs) are a superfamily of integral
transmembrane enzymes that are found in all kingdoms of life. In bacteria, MBOATs modify …