[HTML][HTML] Synthesis and pharmacological activities of pyrazole derivatives: A review
Pyrazole and its derivatives are considered a pharmacologically important active scaffold
that possesses almost all types of pharmacological activities. The presence of this nucleus in …
that possesses almost all types of pharmacological activities. The presence of this nucleus in …
The therapeutic voyage of pyrazole and its analogs: a review
Pyrazole, a five membered heteroaromatic ring with two nitrogen atoms is of immense
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …
Dual or multi-targeting inhibitors: The next generation anticancer agents
NM Raghavendra, D Pingili, S Kadasi, A Mettu… - European journal of …, 2018 - Elsevier
Dual-targeting/Multi-targeting of oncoproteins by a single drug molecule represents an
efficient, logical and alternative approach to drug combinations. An increasing interest in this …
efficient, logical and alternative approach to drug combinations. An increasing interest in this …
Pyrazole scaffold: a remarkable tool in the development of anticancer agents
Pyrazole has been the topic of interest for thousands of researchers across the world
because of its wide spectrum pharmacological activities. Various structural modifications of …
because of its wide spectrum pharmacological activities. Various structural modifications of …
[HTML][HTML] Recent advancement in drug design and discovery of pyrazole biomolecules as cancer and inflammation therapeutics
Pyrazole, an important pharmacophore and a privileged scaffold of immense significance, is
a five-membered heterocyclic moiety with an extensive therapeutic profile, viz., anti …
a five-membered heterocyclic moiety with an extensive therapeutic profile, viz., anti …
Novel pyrazole-5-carboxamide and pyrazole–pyrimidine derivatives: Synthesis and anticancer activity
JB Shi, WJ Tang, R Li, XH Liu - European journal of medicinal chemistry, 2015 - Elsevier
A series of novel pyrazole-5-carboxamide and pyrazole–pyrimidine derivatives were
designed and synthesized. All compounds have been screened for their antiproliferative …
designed and synthesized. All compounds have been screened for their antiproliferative …
[HTML][HTML] Evaluation of substituted pyrazole-based kinase inhibitors in one decade (2011–2020): Current status and future prospects
Pyrazole has been recognized as a pharmacologically important privileged scaffold whose
derivatives produce almost all types of pharmacological activities and have attracted much …
derivatives produce almost all types of pharmacological activities and have attracted much …
Molecular hybrids integrated with benzimidazole and pyrazole structural motifs: Design, synthesis, biological evaluation, and molecular docking studies
R Sivaramakarthikeyan, S Iniyaval, V Saravanan… - ACS …, 2020 - ACS Publications
Synthesis of a series of benzimidazole-ornamented pyrazoles, 6a–6j has been obtained
from arylhydrazine and aralkyl ketones via a multistep synthetic strategy. Among them, a …
from arylhydrazine and aralkyl ketones via a multistep synthetic strategy. Among them, a …
A novel series of thiazolyl–pyrazoline derivatives: Synthesis and evaluation of antifungal activity, cytotoxicity and genotoxicity
In the current work, new thiazolyl–pyrazoline derivatives (1–22) were synthesized and
evaluated for their antifungal effects against pathogenic yeasts and molds using a broth …
evaluated for their antifungal effects against pathogenic yeasts and molds using a broth …
The Synthetic and Biological Attributes of Pyrazole Derivatives: A Review.
Pyrazole nucleus is a unique structural scaffold which acts as an interesting template for
combinatorial as well as medicinal chemistry. This review presents a detailed overview on …
combinatorial as well as medicinal chemistry. This review presents a detailed overview on …