The human body frequently encounters harmful bacterial pathogens and employs immune
defense mechanisms designed to counteract such pathogenic assault. In the adaptive …

Importance Infections due to Staphylococcus aureus are serious complications of
cardiothoracic surgery. A novel vaccine candidate (V710) containing the highly conserved S …

Expressed on epidermal Langerhans cells, CD1a presents a range of self-lipid antigens
found within the skin; however, the extent to which CD1a presents microbial ligands from …

Staphylococcus aureus (SA) is a major bacterial pathogen and causes a wide range of
clinical infections in humans leading to severe outcomes including meningitis, endocarditis …

The skin is an immunocompetent tissue that harbors several kinds of immune cells and a
plethora of commensal microbes constituting the skin microbiome. Staphylococcus aureus is …

The cluster of differentiation 1 (CD1) molecule differs from major histocompatibility complex
class I and II because it presents glycolipid/lipid antigens. Moreover, the CD1-restricted T …

Cluster of differentiation 1 (CD1) is a family of cell-surface glycoproteins that present lipid
antigens to T cells. Humans have five CD1 isoforms. CD1a is distinguished by the small …

The CD1 antigen presenting system is evolutionary conserved and found in mammals, birds
and reptiles. Humans express five isoforms, of which CD1a, CD1b and CD1c represent the …

Methicillin-resistant Staphylococcus aureus (SA) bacteremia is responsible for over 10,000
deaths in the hospital setting each year. Both conventional CD4+ T cells and γδ T cells play …

Purpose: The pathogenesis of thymoma (THYM) remains unclear, and there is no uniform
measurement standard for the complexity of THYM derived from different thymic epithelial …