Overview of bioactive fungal secondary metabolites: cytotoxic and antimicrobial compounds

R Conrado, TC Gomes, GSC Roque, AO De Souza - Antibiotics, 2022 - mdpi.com
Microorganisms are known as important sources of natural compounds that have been
studied and applied for different purposes in distinct areas. Specifically, in the …

Secondary metabolites of fungi from marine habitats

ME Rateb, R Ebel - Natural product reports, 2011 - pubs.rsc.org
Covering: 2006 to mid-2010 Marine-derived fungi continue to produce structurally unique
secondary metabolites, a considerable number of which display promising biological and …

Cryptic metabolites from marine-derived microorganisms using OSMAC and epigenetic approaches

C Pinedo-Rivilla, J Aleu, R Durán-Patrón - Marine Drugs, 2022 - mdpi.com
Marine microorganisms have proven to be a source of new natural products with a wide
spectrum of biological activities relevant in different industrial sectors. The ever-increasing …

Diels–Alder reactions during the biosynthesis of sorbicillinoids

L Kahlert, EF Bassiony, RJ Cox… - Angewandte …, 2020 - Wiley Online Library
The sorbicillinoids are a class of biologically active and structurally diverse fungal
polyketides arising from sorbicillin. Through co‐expression of sorA, sorB, sorC, and sorD …

The sorbicillinoid family of natural products: isolation, biosynthesis, and synthetic studies

AM Harned, KA Volp - Natural product reports, 2011 - pubs.rsc.org
Covering: 1948 up to the end of 2010 The sorbicillinoids are a family of hexaketide
metabolites that have been isolated from a variety of fungal sources, collected from both …

Enzymatic dimerization in the biosynthetic pathway of microbial natural products

J Liu, A Liu, Y Hu - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to August 2020 The dramatic increase in the identification of dimeric natural
products generated by microorganisms and plants has played a significant role in drug …

Novel natural products from extremophilic fungi

X Zhang, SJ Li, JJ Li, ZZ Liang, CQ Zhao - Marine Drugs, 2018 - mdpi.com
Extremophilic fungi have been found to develop unique defences to survive extremes of
pressure, temperature, salinity, desiccation, and pH, leading to the biosynthesis of novel …

Sorbicillinoids from fungi and their bioactivities

J Meng, X Wang, D Xu, X Fu, X Zhang, D Lai, L Zhou… - Molecules, 2016 - mdpi.com
Sorbicillinoids are important hexaketide metabolites derived from fungi. They have a variety
of biological activities including cytotoxic, antioxidant, antiviral and antimicrobial activity. The …

Natural products from thioester reductase containing biosynthetic pathways

MW Mullowney, RA McClure, MT Robey… - Natural product …, 2018 - pubs.rsc.org
Covering: up to 2018 Thioester reductase domains catalyze two-and four-electron
reductions to release natural products following assembly on nonribosomal peptide …

Marine dissolved organic matter: a vast and unexplored molecular space

TS Catalá, S Shorte, T Dittmar - Applied microbiology and biotechnology, 2021 - Springer
Marine dissolved organic matter (DOM) comprises a vast and unexplored molecular space.
Most of it resided in the oceans for thousands of years. It is among the most diverse …