[HTML][HTML] Peptide and peptide-based inhibitors of SARS-CoV-2 entry

D Schütz, YB Ruiz-Blanco, J Münch, F Kirchhoff… - Advanced drug delivery …, 2020 - Elsevier
To date, no effective vaccines or therapies are available against the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), the causative pandemic agent of the coronavirus …

Review and perspective on bioinformatics tools using machine learning and deep learning for predicting antiviral peptides

N Lefin, L Herrera-Belén, JG Farias, JF Beltrán - Molecular diversity, 2024 - Springer
Viruses constitute a constant threat to global health and have caused millions of human and
animal deaths throughout human history. Despite advances in the discovery of antiviral …

Better understanding and prediction of antiviral peptides through primary and secondary structure feature importance

AS Chowdhury, SM Reehl, K Kehn-Hall, B Bishop… - Scientific reports, 2020 - nature.com
The emergence of viral epidemics throughout the world is of concern due to the scarcity of
available effective antiviral therapeutics. The discovery of new antiviral therapies is …

AVPIden: a new scheme for identification and functional prediction of antiviral peptides based on machine learning approaches

Y Pang, L Yao, JH Jhong, Z Wang… - Briefings in …, 2021 - academic.oup.com
Antiviral peptide (AVP) is a kind of antimicrobial peptide (AMP) that has the potential ability
to fight against virus infection. Machine learning-based prediction with a computational …

Deepstacked-AVPs: predicting antiviral peptides using tri-segment evolutionary profile and word embedding based multi-perspective features with deep stacking …

S Akbar, A Raza, Q Zou - BMC bioinformatics, 2024 - Springer
Background Viral infections have been the main health issue in the last decade. Antiviral
peptides (AVPs) are a subclass of antimicrobial peptides (AMPs) with substantial potential to …

A separable temporal convolutional networks based deep learning technique for discovering antiviral medicines

V Singh, SK Singh - Scientific Reports, 2023 - nature.com
An alarming number of fatalities caused by the COVID-19 pandemic has forced the scientific
community to accelerate the process of therapeutic drug discovery. In this regard, the …

Accelerating the discovery of anticancer peptides through deep forest architecture with deep graphical representation

L Yao, W Li, Y Zhang, J Deng, Y Pang… - International Journal of …, 2023 - mdpi.com
Cancer is one of the leading diseases threatening human life and health worldwide. Peptide-
based therapies have attracted much attention in recent years. Therefore, the precise …

[PDF][PDF] Fatimawali

TE Tallei, SG Tumilaar, NJ Niode - Kepel, BJ, 2021 - academia.edu
Before entering the cell, the SARS-CoV-2 spike glycoprotein receptor-binding domain (RBD)
binds to the human angiotensin-converting enzyme 2 (hACE2) receptor. Hence, this RBD is …

D eepafp: an effective computational framework for identifying antifungal peptides based on deep learning

L Yao, Y Zhang, W Li, CR Chung, J Guan… - Protein …, 2023 - Wiley Online Library
Fungal infections have become a significant global health issue, affecting millions
worldwide. Antifungal peptides (AFPs) have emerged as a promising alternative to …

[HTML][HTML] Potential chimeric peptides to block the SARS-CoV-2 spike receptor-binding domain

D Barh, S Tiwari, BS Andrade, M Giovanetti… - …, 2020 - ncbi.nlm.nih.gov
Background: There are no known medicines or vaccines to control the COVID-19 pandemic
caused by SARS-CoV-2 (nCoV). Antiviral peptides are superior to conventional drugs and …