Financial Disclosure Prof. Menon has stock ownership and has received research funding
from Abcodia Ltd, a UCL spinout company with an interest in biomarkers and commercial …

Background: Mutations in breast cancer susceptibility genes (BRCA1 and BRCA2) are
associated with increased risks for breast, ovarian, and other types of cancer. Purpose: To …

Purpose To establish the performance of screening with serum cancer antigen 125 (CA-
125), interpreted using the risk of ovarian cancer algorithm (ROCA), and transvaginal …

Objective To examine the psychological sequelae associated with abnormal screening in
the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). Design …

Background Germline TP53 gene pathogenic variants (pv) cause a very high lifetime risk of
developing cancer, almost 100% for women and 75% for men. In the UK, annual MRI breast …

Screening for pancreatic cancer (PC) in high-risk groups aimed to detect early cancers is
currently done only in the research setting, and data on psychological outcomes of …

Background In the UK there has been an effort, through the National Awareness and Early
Diagnosis Initiative (NAEDI), to increase early stage diagnoses and ultimately cancer …

Objective To investigate psychological correlates in women referred with suspected ovarian
cancer via the fast‐track pathway, explore how anxiety and distress levels change at 12 …

Background In the absence of routine ovarian cancer screening, promoting help-seeking in
response to ovarian symptoms is a potential route to early diagnosis. The factors influencing …

Objective We assessed the feasibility, patient acceptability of and compliance of a new
surveillance strategy for ovarian cancer surveillance in women with BRCA mutations, based …