The role of extracellular vesicles in COVID-19 virus infection

M Hassanpour, J Rezaie, M Nouri, Y Panahi - Infection, Genetics and …, 2020 - Elsevier
Extracellular vesicles releasing from various types of cells contribute to intercellular
communication via delivering bio-molecules like nucleic acids, proteins, and lipids to …

Conditioned medium of mesenchymal stromal cells: a new class of therapeutics

NV Bogatcheva, ME Coleman - Biochemistry (Moscow), 2019 - Springer
Mesenchymal stromal cell (MSCs) represent a class of biologics with the prospects for
employment as immunomodulatory, tissue-protective, and regenerative therapeutics. In …

Mesenchymal stem cells for critical limb ischemia: their function, mechanism, and therapeutic potential

LV Lozano Navarro, X Chen… - Stem cell research & …, 2022 - Springer
Peripheral arterial disease is atherosclerotic occlusive disease of the lower extremity
arteries and afflicts hundreds of millions of individuals worldwide. Its most severe …

Unraveling the therapeutic effects of mesenchymal stem cells in asthma

F Mirershadi, M Ahmadi, A Rezabakhsh… - Stem Cell Research & …, 2020 - Springer
Asthma is a chronic inflammatory disease associated with airway hyper-responsiveness,
chronic inflammatory response, and excessive structural remodeling. The current …

[HTML][HTML] Dendritic cells and M2 macrophage play an important role in suppression of Th2-mediated inflammation by adipose stem cells-derived extracellular vesicles

KS Cho, SA Kang, SD Kim, SJ Mun, HS Yu, HJ Roh - Stem Cell Research, 2019 - Elsevier
Although stem cell-derived extracellular vesicles (EVs) have been shown to facilitate
regeneration of injured tissue, there is no report that evaluates the immune-modulating effect …

Cardiac cell therapy for heart repair: should the cells be left out?

D Zhu, K Cheng - Cells, 2021 - mdpi.com
Cardiovascular disease (CVD) is still the leading cause of death worldwide. Coronary artery
occlusion, or myocardial infarction (MI) causes massive loss of cardiomyocytes. The …

Systemic delivery of mesenchymal stem cells condition media in repeated doses acts as magic bullets in restoring IFN-γ/IL-4 balance in asthmatic rats

R Keyhanmanesh, R Rahbarghazi, MR Aslani… - Life sciences, 2018 - Elsevier
Aims With respect to recent advantage in stem cell application, given the concern reported
previously after stem cell transplantation, mesenchymal stem cell-derived conditioned media …

Bone marrow mesenchymal stem cells and condition media diminish inflammatory adhesion molecules of pulmonary endothelial cells in an ovalbumin-induced …

R Rahbarghazi, R Keyhanmanesh, MR Aslani… - Microvascular …, 2019 - Elsevier
Objectives Although excitements related to stem cell therapeutic outcomes have been
highlighted enormously in asthma, the vast majority of works were conducted by researchers …

Cellular therapy for the treatment of paediatric respiratory disease

LC Brennan, A O'Sullivan, R MacLoughlin - International Journal of …, 2021 - mdpi.com
Respiratory disease is the leading cause of death in children under the age of 5 years old.
Currently available treatments for paediatric respiratory diseases including …

Mesenchymal stromal cell conditioned media for lung disease: a systematic review and meta-analysis of preclinical studies

C Emukah, E Dittmar, R Naqvi, J Martinez, A Corral… - Respiratory …, 2019 - Springer
Background Inflammation plays an important role in the pathogenesis of many lung
diseases. Preclinical studies suggest that mesenchymal stromal cell (MSC) conditioned …