Extensive debates continue regarding marijuana (Cannabis spp), the most commonly used
illicit substance in many countries worldwide. There has been an exponential increase of …

Introduction: The complexity of the endocannabinoid (eCB) system is becoming better
understood and new drivers of eCB signaling are emerging. Modulation of the activities of …

Abstract 5F-MDMB-PICA has been detected in products sold on the internet as well as in
biological samples since 2016. It is associated with serious adverse health and behavioral …

Synthetic cannabinoid (SC) products have gained popularity as abused drugs over the past
decade in many countries. The SCs broadly impact psychological state (eg, mood, suicidal …

With rising rates of cannabis use in the general population and an increasing number of US
states legalizing both recreational and medical cannabis use, it is important to be informed …

Abstract Purpose of Review To summarize the current literature on the effects of
cannabinoids in humans and to discuss the existing literature on the sex-and gender-related …

Background: Synthetic cannabinoids are, typically, full agonists at the cannabinoid CB1
receptor, and therefore considerably more potent than natural cannabis and may have …

The term schizophrenia describes a group of multifaceted psychiatric conditions causing
significant impairment of the quality of life of affected patients. Although multiple …

Endogenous and exogenous cannabinoids bind to central cannabinoid receptors to control
a multitude of behavioral functions, including aggression. The first main objective of this …

A substantial body of credible evidence has accumulated that suggest that cannabis use is
an important potentially preventable risk factor for the development of psychotic illness and …