Molecular interactions and functions of IL-32

KR Aass, MH Kastnes, T Standal - Journal of Leucocyte Biology, 2021 - academic.oup.com
IL-32 is a multifaceted cytokine associated with several diseases and inflammatory
conditions. Its expression is induced in response to cellular stress such as hypoxia …

The research progress in immunotherapy of tuberculosis

J Mi, Y Liang, J Liang, W Gong, S Wang… - Frontiers in cellular …, 2021 - frontiersin.org
Tuberculosis (TB) is a serious public health problem worldwide. The combination of various
anti-TB drugs is mainly used to treat TB in clinical practice. Despite the availability of …

NK-like CD8+ γδ T cells are expanded in persistent Mycobacterium tuberculosis infection

R Roy Chowdhury, JR Valainis, M Dubey… - Science …, 2023 - science.org
The response of gamma delta (γδ) T cells in the acute versus chronic phases of the same
infection is unclear. How γδ T cells function in acute Mycobacterium tuberculosis (Mtb) …

Extracellular vesicle IL-32 promotes the M2 macrophage polarization and metastasis of esophageal squamous cell carcinoma via FAK/STAT3 pathway

Y Sun, Y Qian, C Chen, H Wang, X Zhou… - Journal of Experimental …, 2022 - Springer
Background Metastasis is the leading cause of mortality in human cancers, including
esophageal squamous cell carcinoma (ESCC). As a pro-inflammatory cytokine, IL-32 was …

IFN-γ independent markers of Mycobacterium tuberculosis exposure among male South African gold miners

LRL Davies, MT Smith, D Cizmeci, S Fischinger… - …, 2023 - thelancet.com
Background The prevalence of tuberculosis among men who work in the gold mines of
South Africa is among the highest in the world, but a fraction of miners demonstrate …

Interleukin 32 as a potential marker for diagnosis of tuberculous pleural effusion

J Du, MM Shao, FS Yi, ZY Huang, X Qiao… - Microbiology …, 2022 - Am Soc Microbiol
Accurate differential diagnosis is the key to choosing the correct treatment for pleural
effusion. The present study aimed to assess whether interleukin 32 (IL-32) could be a new …

IL32: The multifaceted and unconventional cytokine

A Gautam, B Pandit - Human Immunology, 2021 - Elsevier
Interleukin 32 is a unique intracellular cytokine which affects many cellular and physiological
functions like cell death and survival, inflammation and response to pathogens. With …

REL and BHLHE40 variants are associated with IL-12 and IL-10 responses and tuberculosis risk

JA Shah, AJ Warr, AD Graustein, A Saha… - The Journal of …, 2022 - journals.aai.org
The major human genes regulating Mycobacterium tuberculosis–induced immune
responses and tuberculosis (TB) susceptibility are poorly understood. Although IL-12 and IL …

[PDF][PDF] 干扰素γ, 白细胞介素-32 及涎液化糖链抗原6 水平检测在肺结核治疗转归中的评估作用

韩伟, 潘艳静, 李秀芳, 黄健, 高盼盼, 崔俊伟 - 临床内科杂志, 2023 - lcnkzz.com
目的研究干扰素γ (IFN⁃ γ), 白细胞介素⁃ 32 (IL⁃ 32) 及涎液化糖链抗原6 (KL⁃ 6)
水平检测在肺结核治疗转归中的评估作用. 方法纳入肺结核患者84 例(研究组) …

Interleukin‐32γ in the Control of Acute Experimental Chagas Disease

YLL Braga, JRC Neto, AWF Costa… - Journal of …, 2022 - Wiley Online Library
Chagas disease (CD) is an important parasitic disease caused by Trypanosoma cruzi.
Interleukin‐32 (IL‐32) plays an important role in inflammation and in the development of …