Pathogen at the gates: human cytomegalovirus entry and cell tropism
The past few years have brought substantial progress toward understanding how human
cytomegalovirus (HCMV) enters the remarkably wide spectrum of cell types and tissues that …
cytomegalovirus (HCMV) enters the remarkably wide spectrum of cell types and tissues that …
Cytomegalovirus: pathogen, paradigm, and puzzle
M Boeckh, AP Geballe - The Journal of clinical investigation, 2011 - Am Soc Clin Investig
Human cytomegalovirus (CMV), one of the eight herpesviruses that commonly infect
humans, is best known for its propensity to cause disease in immunocompromised patients …
humans, is best known for its propensity to cause disease in immunocompromised patients …
Human cytomegalovirus immunity and immune evasion
SE Jackson, GM Mason, MR Wills - Virus research, 2011 - Elsevier
Human cytomegalovirus (HCMV) infection induces both innate immune responses including
Natural Killer cells as well as adaptive humoral and cell mediated (CD4+ helper, CD8+ …
Natural Killer cells as well as adaptive humoral and cell mediated (CD4+ helper, CD8+ …
Reconstruction of the complete human cytomegalovirus genome in a BAC reveals RL13 to be a potent inhibitor of replication
RJ Stanton, K Baluchova, DJ Dargan… - The Journal of …, 2010 - Am Soc Clin Investig
Human cytomegalovirus (HCMV) in clinical material cannot replicate efficiently in vitro until it
has adapted by mutation. Consequently, wild-type HCMV differ fundamentally from the …
has adapted by mutation. Consequently, wild-type HCMV differ fundamentally from the …
Human cytomegalovirus: taking the strain
In celebrating the 60th anniversary of the first isolation of human cytomegalovirus (HCMV),
we reflect on the merits and limitations of the viral strains currently being used to develop …
we reflect on the merits and limitations of the viral strains currently being used to develop …
Genomic and geographical structure of human cytomegalovirus
OJ Charles, C Venturini, S Gantt… - Proceedings of the …, 2023 - National Acad Sciences
Human cytomegalovirus (CMV) has infected humans since the origin of our species and
currently infects most of the world's population. Variability between CMV genomes is the …
currently infects most of the world's population. Variability between CMV genomes is the …
High-throughput analysis of human cytomegalovirus genome diversity highlights the widespread occurrence of gene-disrupting mutations and pervasive …
S Sijmons, K Thys, M Mbong Ngwese… - Journal of …, 2015 - Am Soc Microbiol
Human cytomegalovirus is a widespread pathogen of major medical importance. It causes
significant morbidity and mortality in immunocompromised individuals, and congenital …
significant morbidity and mortality in immunocompromised individuals, and congenital …
Specific capture and whole-genome sequencing of viruses from clinical samples
Whole genome sequencing of viruses directly from clinical samples is integral for
understanding the genetics of host-virus interactions. Here, we report the use of sample …
understanding the genetics of host-virus interactions. Here, we report the use of sample …
Where do we stand after decades of studying human cytomegalovirus?
F Gugliesi, A Coscia, G Griffante, G Galitska… - Microorganisms, 2020 - mdpi.com
Human cytomegalovirus (HCMV), a linear double-stranded DNA betaherpesvirus belonging
to the family of Herpesviridae, is characterized by widespread seroprevalence, ranging …
to the family of Herpesviridae, is characterized by widespread seroprevalence, ranging …
Human cytomegalovirus genomes sequenced directly from clinical material: variation, multiple-strain infection, recombination, and gene loss
The genomic characteristics of human cytomegalovirus (HCMV) strains sequenced directly
from clinical pathology samples were investigated, focusing on variation, multiple-strain …
from clinical pathology samples were investigated, focusing on variation, multiple-strain …