Degradable controlled-release polymers and polymeric nanoparticles: mechanisms of controlling drug release

N Kamaly, B Yameen, J Wu, OC Farokhzad - Chemical reviews, 2016 - ACS Publications
The development of biodegradable polymers represents a revolution in medicine spanning
over 50 years and leading to significant biotechnological advancements in drug delivery …

[HTML][HTML] Hollow microneedle assisted intradermal delivery of hypericin lipid nanocapsules with light enabled photodynamic therapy against skin cancer

H Abd-El-Azim, IA Tekko, A Ali, A Ramadan… - Journal of Controlled …, 2022 - Elsevier
Photodynamic therapy (PDT) to manage non-melanoma skin cancers has garnered great
attention over the past few years. Hypericin (Hy) is a potent lipid-soluble photosensitiser with …

Current advances in development of new docetaxel formulations

E Zhang, R Xing, S Liu, P Li - Expert Opinion on Drug Delivery, 2019 - Taylor & Francis
Introduction: Docetaxel (DTX) is one of the most important chemotherapeutic agents and has
been widely used for treatment of various types of cancers. However, the clinical …

Ultralong circulating lollipop‐like nanoparticles assembled with gossypol, doxorubicin, and polydopamine via π–π stacking for synergistic tumor therapy

Y Wang, Y Wu, K Li, S Shen, Z Liu… - Advanced Functional …, 2019 - Wiley Online Library
Long blood circulation in vivo remains a challenge to dual‐drug‐loaded nanocarriers for
synergistic chemotherapy. Herein, a novel strategy to prepare lollipop‐like dual‐drug …

Barriers to the intestinal absorption of four insulin-loaded arginine-rich nanoparticles in human and rat

P Lundquist, G Khodus, Z Niu, LN Thwala… - ACS …, 2022 - ACS Publications
Peptide drugs and biologics provide opportunities for treatments of many diseases.
However, due to their poor stability and permeability in the gastrointestinal tract, the oral …

Self-assembled hyaluronan nanocapsules for the intracellular delivery of anticancer drugs

A Cadete, A Olivera, M Besev, PK Dhal, L Gonçalves… - Scientific Reports, 2019 - nature.com
Preparation of sophisticated delivery systems for nanomedicine applications generally
involve multi-step procedures using organic solvents. In this study, we have developed a …

Curcumin-loaded nanoemulsion: A new safe and effective formulation to prevent tumor reincidence and metastasis

S Guerrero, M Inostroza-Riquelme… - Nanoscale, 2018 - pubs.rsc.org
Curcumin is widely considered beneficial to human health, but insolubility and instability
greatly hamper reproducible exploitation of the advantageous traits. Here we report on the …

Synthesis, self-assembly and anticancer drug encapsulation and delivery properties of cyclodextrin-based giant amphiphiles

L Gallego-Yerga, C de la Torre, F Sansone… - Carbohydrate …, 2021 - Elsevier
Cyclodextrin-calixarene giant amphiphiles that can self-assemble into nanospheres or
nanovesicles have the ability to encapsulate the anticancer hydrophobic drugs docetaxel …

Membrane fluidity as a new means to selectively target cancer cells with fusogenic lipid carriers

J Bompard, A Rosso, L Brizuela, S Mebarek, LJ Blum… - Langmuir, 2020 - ACS Publications
Lipid-based carriers such as liposomes represent one of the most advanced classes of drug
delivery systems. Their clinical success relies on their composition, similar to that of the cell …

[HTML][HTML] Rational design of polyarginine nanocapsules intended to help peptides overcoming intestinal barriers

Z Niu, E Tedesco, F Benetti, A Mabondzo… - Journal of Controlled …, 2017 - Elsevier
The aim of this work was to rationally design and characterize nanocapsules (NCs)
composed of an oily core and a polyarginine (PARG) shell, intended for oral peptide …