Updated information on antimicrobial activity of hydrazide–hydrazones

Ł Popiołek - International Journal of Molecular Sciences, 2021 - mdpi.com
Hydrazide–hydrazones possess a wide spectrum of bioactivity, including antibacterial,
antitubercular, antifungal, anticancer, anti-inflammatory, anticonvulsant, antidepressant …

Coumarin hybrid derivatives as promising leads to treat tuberculosis: Recent developments and critical aspects of structural design to exhibit anti-tubercular activity

DS Reddy, M Kongot, A Kumar - Tuberculosis, 2021 - Elsevier
Tuberculosis (TB) is a highly contagious airborne disease with nearly 25% of the world's
population infected with it. Challenges such as multi drug resistant TB (MDR-TB), extensive …

Coumarin-benzothiazole based azo dyes: synthesis, characterization, computational, photophysical and biological studies

B Manjunatha, YD Bodke, O Nagaraja… - Journal of Molecular …, 2021 - Elsevier
In this paper, we have reported the synthesis of some coumarin-benzothiazole based azo
dyes (C 1-C 5). The structure of the synthesised dyes was precisely established from their …

Recent advances in anti-tuberculosis drug discovery based on hydrazide–hydrazone and thiadiazole derivatives targeting inhA

Y Teneva, R Simeonova, V Valcheva, VT Angelova - Pharmaceuticals, 2023 - mdpi.com
Tuberculosis is an extremely serious problem of global public health. Its incidence is
worsened by the presence of multidrug-resistant (MDR) strains of Mycobacterium …

Synthesis of coumarin-thioether conjugates as potential anti-tubercular agents: Their molecular docking and X-ray crystal studies

M Akki, DS Reddy, KS Katagi, A Kumar… - Journal of Molecular …, 2022 - Elsevier
In this work, we report a series of 4-(2, 6-dimethylphenyl) thio) methyl)-2H-chromen-2-one
conjugates as promising leads to treat tuberculosis. Spectroscopic and other analytical …

Design, synthesis, antioxidant and anticholinesterase activities of novel isonicotinic hydrazide-hydrazone derivatives

Ö Aslanhan, E Kalay, FS Tokalı, Z Can… - Journal of Molecular …, 2023 - Elsevier
The design and synthesis of hydrazone derivatives are increasing in popularity day by day
due to the significant biological activities of this scaffold. In the present study, twelve novel …

Synthesis, in silico and in vitro analysis of hydrazones as potential antituberculosis agents

BR Thorat, SN Mali, D Rani… - Current Computer-Aided …, 2021 - ingentaconnect.com
Tuberculosis (TB) is a major cause of mortality and illness as reported by the WHO in 2019.
The WHO report also mentioned the fact that about 10.0 million people fell ill with …

Synthesis, admetSAR predictions, DPPH radical scavenging activity, and potent anti-mycobacterial studies of hydrazones of substituted 4-(anilino methyl) …

VJ Desale, SN Mali, BR Thorat… - … Computer-Aided Drug …, 2021 - ingentaconnect.com
Background: For the past several decades, the presence of tuberculosis (TB) is being
remarked as the most common infectious disease leading to mortality. Objective: Hydrazone …

Development of new antimycobacterial sulfonyl hydrazones and 4-methyl-1, 2, 3-thiadiazole-based hydrazone derivatives

VT Angelova, T Pencheva, N Vassilev, E K-Yovkova… - Antibiotics, 2022 - mdpi.com
Fifteen 4-methyl-1, 2, 3-thiadiazole-based hydrazone derivatives 3a–d and sulfonyl
hydrazones 5a–k were synthesized. They were characterized by 1H-NMR, 13C NMR, and …

Structural investigations of new tridentate-phenylacetohydrazide Schiff base metal chelates: X-ray diffraction, Hirshfeld surface analyses, DFT, antibacterial and …

FM Elantabli, RG Mohamed, SM El-Medani… - Journal of Molecular …, 2024 - Elsevier
The coordination complexes of a tridentate-phenylacetohydrazide Schiff base (2-
hydroxybenzylidene-2-phenylacetohydrazide, HL) with metal ions, namely, iron (II), zinc (II) …