Wall shear stress and its role in atherosclerosis
M Zhou, Y Yu, R Chen, X Liu, Y Hu, Z Ma… - Frontiers in …, 2023 - frontiersin.org
Atherosclerosis (AS) is the major form of cardiovascular disease and the leading cause of
morbidity and mortality in countries around the world. Atherosclerosis combines the …
morbidity and mortality in countries around the world. Atherosclerosis combines the …
The glycocalyx and its role in vascular physiology and vascular related diseases
Purpose In 2007 the two senior authors wrote a review on the structure and function of the
endothelial glycocalyx layer (Weinbaum in Annu Rev Biomed Eng 9: 121–167, 2007). Since …
endothelial glycocalyx layer (Weinbaum in Annu Rev Biomed Eng 9: 121–167, 2007). Since …
Investigation of wall shear stress in cardiovascular research and in clinical practice—from bench to bedside
K Urschel, M Tauchi, S Achenbach, B Dietel - International Journal of …, 2021 - mdpi.com
In the 1900s, researchers established animal models experimentally to induce
atherosclerosis by feeding them with a cholesterol-rich diet. It is now accepted that high …
atherosclerosis by feeding them with a cholesterol-rich diet. It is now accepted that high …
The role of endothelial surface glycocalyx in mechanosensing and transduction
The endothelial cells (ECs) forming the inner wall of every blood vessel are constantly
exposed to the mechanical forces generated by blood flow. The EC responses to these …
exposed to the mechanical forces generated by blood flow. The EC responses to these …
Pumped and pumpless microphysiological systems to study (nano) therapeutics
Fluidic microphysiological systems (MPS) are microfluidic cell culture devices that are
designed to mimic the biochemical and biophysical in vivo microenvironments of human …
designed to mimic the biochemical and biophysical in vivo microenvironments of human …
The story of wall shear stress in coronary artery atherosclerosis: biochemical transport and mechanotransduction
M Mahmoudi, A Farghadan… - Journal of …, 2021 - asmedigitalcollection.asme.org
Coronary artery atherosclerosis is a local, multifactorial, complex disease, and the leading
cause of death in the US. Complex interactions between biochemical transport and …
cause of death in the US. Complex interactions between biochemical transport and …
The role of glycocalyx and caveolae in vascular homeostasis and diseases
SR Potje, TDC Paula, M Paulo… - Frontiers in Physiology, 2021 - frontiersin.org
This review highlights recent findings about the role that endothelial glycocalyx and
caveolae play in vascular homeostasis. We describe the structure, synthesis, and function of …
caveolae play in vascular homeostasis. We describe the structure, synthesis, and function of …
Hemodynamic and morphological characteristics of a growing cerebral aneurysm
The growth of cerebral aneurysms is linked to local hemodynamic conditions, but the driving
mechanisms of the growth are poorly understood. The goal of this study was to examine the …
mechanisms of the growth are poorly understood. The goal of this study was to examine the …
Vascular endothelial cell behavior in complex mechanical microenvironments
The vascular mechanical microenvironment consists of a mixture of spatially and temporally
changing mechanical forces. This exposes vascular endothelial cells to both hemodynamic …
changing mechanical forces. This exposes vascular endothelial cells to both hemodynamic …
Modelling how curved active proteins and shear flow pattern cellular shape and motility
Cell spreading and motility on an adhesive substrate are driven by the active physical forces
generated by the actin cytoskeleton. We have recently shown that coupling curved …
generated by the actin cytoskeleton. We have recently shown that coupling curved …