How do we understand neuronal signaling in the brain, how neurons control behavior, or
how signaling malfunctions during disease? Neuroscientists might take two approaches …

The study of subcellular targets and biochemical processes within a living cell is valuable for
biological and medical research. Secretory vesicles, one such important intracellular target …

Many biological systems contain an ensemble of cells with heterogeneous chemistry;
therefore, it is important to analyze them on an individual basis in order to elucidate the role …

Thin-film platinum ultramicroelectrode arrays (MEAs) with subcellular microelectrodes were
developed for the spatial measurement of neurotransmitter release across single cells or …

Indium tin oxide (ITO), as an electrode, has superiority over metal electrodes commonly
used for electroanalysis due to its low cost, low electrochemical background response, wide …

The effect of latrunculin A, an inhibitor of actin cross-linking, on exocytosis in PC12 cells was
investigated with single cell amperometry. This analysis strongly suggests that the actin …

The number of scientific disciplines whose names begin with the prefix nano has grown
dramatically since the launch of the National Nanotechnology Initiative in 2000. Some of …

Real-time investigations of neurotransmitter release provide a direct insight on the
mechanisms involved in synaptic communication. Carbon fiber microelectrodes are state-of …

For the measurement of events of dopamine (DA) release as well as the coordinating
neurotransmission in the nerve system, a neural microelectrode array (nMEA) …

We report the fabrication and characterization of microwell-based individually addressable
microelectrode arrays (MEAs) and their application to spatially and temporally resolved …