Astrocytes are the most abundant cell type within the central nervous system. They play
essential roles in maintaining normal brain function, as they are a critical structural and …

Melatonin is an ancient molecule that is evident in high concentrations in various tissues
throughout the body. It can be separated into two pools; one of which is synthesized by the …

The incidence and prevalence of neurodegenerative diseases (ND) increase with life
expectancy. This paper reviews the role of oxidative stress (OS) in ND and pharmacological …

Toxins that pass through the blood-brain barrier put neurons and glia in peril. The damage
inflicted is usually a consequence of the ability of these toxic agents to induce free radical …

Oxidative stress, in which production of highly reactive oxygen species (ROS) and reactive
nitrogen species (RNS) overwhelms antioxidant defenses, is a feature of many neurological …

Sleep deprivation (SD) has been shown to induce oxidative stress which causes cognitive
impairment. Melatonin, an endogenous potent antioxidant, protects neurons from oxidative …

The aim of this study was designed to investigate the possible beneficial effects of Nigella
sativa (NS) and derived thymoquinone (TQ) on neurodegeneration in hippocampus after …

Hyperglycemia plays a critical role in the development and progression of diabetic
neuropathy. One of the mechanisms by which hyperglycemia causes neural degeneration is …

Acrylamide (ACR) is an industrial pollutant, to which humans are exposed through
chemicals associated with day to day human life and contributes to neurological disorders …

Proton magnetic resonance spectroscopy (1H MRS) is a noninvasive imaging technique that
permits measurement of particular compounds or metabolites within the tissue of interest. In …