Multi-modality contrast and brightfield context rendering for enhanced pathology determination and multi-analyte detection in tissue

K Garsha, G Pestano, M Otter, AD Nagy… - US Patent …, 2016 - Google Patents
(73) Assignee: VENTANA MEDICAL SYSTEMS, INC. Tucson, AZ (US) Cellular context in
epigenetics: Quantitative multicolor imaging and (*) Notice: Subject to any disclaimer, the …

Image processing method and system for analyzing a multi-channel image obtained from a biological tissue sample being stained by multiple stains

M Barnes, C Bifulco, T Chen, A Tubbs - US Patent 10,275,880, 2019 - Google Patents
Systems and methods for automatic FOV selection in immunoscore computation that involve
reading images for individual markers from an unmixed multiplex slide or single stain slides …

Viewers and related methods, systems and circuits with patch gallery user interfaces

J Molin, C Lundström - US Patent 10,489,633, 2019 - Google Patents
Methods, systems, workstations, and computer programs with user interactive patch gallery
user interfaces that allow a user to alter at least one feature dimension of the patches and/or …

Segmentation of Biological Image Data

S Krishnan - US Patent App. 13/109,457, 2011 - Google Patents
BACKGROUND 0003. The expression of biologically relevant features (eg, type, size, and
density of cells) often forms the basis of diagnosis and treatment. Typically, a trained …

Method, system and computer program product for breast density classification using parts-based local features

L Ghouti, AH Owaidh - US Patent 9,519,966, 2016 - Google Patents
The present invention relates to a method, a system and a computer program product for the
classification of breast density from mammographic imagery. Specifically, the invention …

Methods, systems and circuits for generating magnification-dependent images suitable for whole slide images

J Molin, C Lundstrom, KS Devan - US Patent 9,412,162, 2016 - Google Patents
Methods, systems, workstations, computer programs visually enhance features of interest in
an obtained image that are otherwise only visually apparent in a high magnification sub …

Descriptive measurements and quantification of staining artifacts for in situ hybridization

K Garsha, M Otter, J Taft, B Stevens… - US Patent 10,614,284, 2020 - Google Patents
Immunohistochemistry (IHC) and in situ hybridization (ISH) have the aim of detecting,
localizing and quantifying certain analytes for various diagnostic purposes. The quality of the …

Biomarker evaluation through image analysis

M Athelogou, G Binnig, G Schmidt - US Patent 9,466,103, 2016 - Google Patents
A method for determining whether a test biomarker is a stain for a type of cell component,
Such as membrane or nucleus, involves performing various segmentation processes on an …

Pattern change discovery between high dimensional data sets

Y Xu, ZM Zhang - US Patent 11,947,622, 2024 - Google Patents
The general problem of pattern change discovery between high-dimensional data sets is
addressed by considering the notion of the principal angles between the subspaces is …

Color unmixing with scatter correction

Y Nie - US Patent 11,107,248, 2021 - Google Patents
The present disclosure provides systems and methods for separating colors in an image by
automatically selecting color reference vectors that take into consideration the effect of light …