[HTML][HTML] Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes
M Deponte - Biochimica et Biophysica Acta (BBA)-General Subjects, 2013 - Elsevier
BACKGROUND: Glutathione-dependent catalysis is a metabolic adaptation to chemical
challenges encountered by all life forms. In the course of evolution, nature optimized …
challenges encountered by all life forms. In the course of evolution, nature optimized …
Glutathione transferases
JD Hayes, JU Flanagan… - Annu. Rev. Pharmacol …, 2005 - annualreviews.org
▪ Abstract This review describes the three mammalian glutathione transferase (GST)
families, namely cytosolic, mitochondrial, and microsomal GST, the latter now designated …
families, namely cytosolic, mitochondrial, and microsomal GST, the latter now designated …
Glutathione transferases in the genomics era: new insights and perspectives
C Frova - Biomolecular engineering, 2006 - Elsevier
In the last decade the tumultuous development of “omics” greatly improved our ability to
understand protein structure, function and evolution, and to define their roles and networks …
understand protein structure, function and evolution, and to define their roles and networks …
Glutathione transferases in bacteria
Bacterial glutathione transferases (GSTs) are part of a superfamily of enzymes that play a
key role in cellular detoxification. GSTs are widely distributed in prokaryotes and are …
key role in cellular detoxification. GSTs are widely distributed in prokaryotes and are …
Plant glutathione transferases
Soluble plant glutathione transferases (GSTs) consist of seven distinct classes, six of which
have been functionally characterized. The phi and tau class GSTs are specific to plants and …
have been functionally characterized. The phi and tau class GSTs are specific to plants and …
[HTML][HTML] Glutathione and peroxisome redox homeostasis
Despite intensive research on peroxisome biochemistry, the role of glutathione in
peroxisomal redox homeostasis has remained a matter of speculation for many years, and …
peroxisomal redox homeostasis has remained a matter of speculation for many years, and …
Members of the chloride intracellular ion channel protein family demonstrate glutaredoxin-like enzymatic activity
The Chloride Intracellular Ion Channel (CLIC) family consists of six evolutionarily conserved
proteins in humans. Members of this family are unusual, existing as both monomeric soluble …
proteins in humans. Members of this family are unusual, existing as both monomeric soluble …
Oxidative stress in Caenorhabditis elegans: protective effects of the Omega class glutathione transferase (GSTO‐1)
C Burmeister, K Lüersen, A Heinick… - The FASEB …, 2008 - Wiley Online Library
To elucidate the function of Omega class glutathione transferases (GSTs)(EC 2.5. 1.18) in
multicellular organisms, the GSTO‐1 from Caenorhabditis elegans (GSTO‐1; C29E4. 7) was …
multicellular organisms, the GSTO‐1 from Caenorhabditis elegans (GSTO‐1; C29E4. 7) was …
Saccharomyces cerevisiae cells have three Omega class glutathione S-transferases acting as 1-Cys thiol transferases
A Garcerá, L Barreto, L Piedrafita, J Tamarit… - Biochemical …, 2006 - portlandpress.com
The Saccharomyces cerevisiae genome encodes three proteins that display similarities with
human GSTOs (Omega class glutathione S-transferases) hGSTO1-1 and hGSTO2-2. The …
human GSTOs (Omega class glutathione S-transferases) hGSTO1-1 and hGSTO2-2. The …
The yeast prion protein Ure2 shows glutathione peroxidase activity in both native and fibrillar forms
M Bai, JM Zhou, S Perrett - Journal of Biological Chemistry, 2004 - ASBMB
Ure2p is the precursor protein of the Saccharomyces cerevisiae prion [URE3]. Ure2p shows
homology to glutathione transferases but lacks typical glutathione transferase activity. A …
homology to glutathione transferases but lacks typical glutathione transferase activity. A …