Machine learning and deep learning methods for skin lesion classification and diagnosis: a systematic review
Computer-aided systems for skin lesion diagnosis is a growing area of research. Recently,
researchers have shown an increasing interest in developing computer-aided diagnosis …
researchers have shown an increasing interest in developing computer-aided diagnosis …
Merkel cell carcinoma
Merkel cell carcinoma (MCC) is a rare but highly aggressive skin cancer with
neuroendocrine features. MCC pathogenesis is associated with either the presence of …
neuroendocrine features. MCC pathogenesis is associated with either the presence of …
Efficacy and safety of first-line avelumab treatment in patients with stage IV metastatic Merkel cell carcinoma: a preplanned interim analysis of a clinical trial
SP D'Angelo, J Russell, C Lebbé, B Chmielowski… - JAMA …, 2018 - jamanetwork.com
Importance Merkel cell carcinoma (MCC) is an aggressive skin cancer that is associated
with poor survival outcomes in patients with distant metastatic disease. Results of part A of …
with poor survival outcomes in patients with distant metastatic disease. Results of part A of …
Combined nivolumab and ipilimumab with or without stereotactic body radiation therapy for advanced Merkel cell carcinoma: a randomised, open label, phase 2 trial
Background Merkel cell carcinoma is among the most aggressive and lethal of primary skin
cancers, with a high rate of distant metastasis. Anti-programmed death receptor 1 (anti-PD …
cancers, with a high rate of distant metastasis. Anti-programmed death receptor 1 (anti-PD …
Updated efficacy of avelumab in patients with previously treated metastatic Merkel cell carcinoma after≥ 1 year of follow-up: JAVELIN Merkel 200, a phase 2 clinical …
HL Kaufman, JS Russell, O Hamid, S Bhatia… - … for immunotherapy of …, 2018 - Springer
Background Merkel cell carcinoma (MCC) is a rare, aggressive skin cancer associated with
poor survival outcomes in patients with distant metastatic disease (mMCC). In an initial …
poor survival outcomes in patients with distant metastatic disease (mMCC). In an initial …
The emerging role of miRNAs in Merkel cell carcinoma pathogenesis: Signaling pathway crosstalk
Merkel cell carcinoma (MCC) is an uncommon invasive form of skin cancer that typically
manifests as a nodule on the face, head, or neck that is flesh-colored or bluish-red in …
manifests as a nodule on the face, head, or neck that is flesh-colored or bluish-red in …
[HTML][HTML] Avelumab in patients with previously treated metastatic Merkel cell carcinoma: long-term data and biomarker analyses from the single-arm phase 2 JAVELIN …
Background Merkel cell carcinoma (MCC) is a rare, aggressive skin cancer associated with
a high risk of metastasis. In 2017, avelumab (anti–programmed death-ligand 1 (PD-L1)) …
a high risk of metastasis. In 2017, avelumab (anti–programmed death-ligand 1 (PD-L1)) …
The biology and treatment of Merkel cell carcinoma: current understanding and research priorities
PW Harms, KL Harms, PS Moore… - Nature reviews Clinical …, 2018 - nature.com
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer associated with
advanced age and immunosuppression. Over the past decade, an association has been …
advanced age and immunosuppression. Over the past decade, an association has been …
Phase I study of single-agent utomilumab (PF-05082566), a 4-1BB/CD137 agonist, in patients with advanced cancer
Abstract Purpose: Utomilumab (PF-05082566) is an agonistic mAb that engages the
immune costimulatory molecule 4-1BB/CD137. In this first-in-human, phase I, open-label …
immune costimulatory molecule 4-1BB/CD137. In this first-in-human, phase I, open-label …
Advances in the diagnosis and management of well-differentiated neuroendocrine neoplasms
Neuroendocrine neoplasms constitute a diverse group of tumors that derive from the
sensory and secretory neuroendocrine cells and predominantly arise within the pulmonary …
sensory and secretory neuroendocrine cells and predominantly arise within the pulmonary …