Langerhans cell histiocytosis (LCH) can affect children and adults with a wide variety of
clinical manifestations, including unifocal, single-system multifocal, single-system pulmonary …

Simple Summary Rosai–Dorfman disease (RDD) was a benign histiocytic proliferative
disorder rather than a neoplastic process. Emergent molecular studies have shown …

ALK-positive histiocytosis is a rare subtype of histiocytic neoplasm first described in 2008 in
3 infants with multisystemic disease involving the liver and hematopoietic system. This entity …

Lymphadenopathy occurring in patients with immunoglobulin G4 (IgG4)-related disease,
termed IgG4-related lymphadenopathy, shows morphologic heterogeneity and overlap with …

Malignant histiocytoses (MHs), or the 'M group'of the Histiocyte Society classification, are
characterized by neoplastic histiocytes with large pleomorphic nuclei. MH encompasses the …

Activating mutations in the mitogen-activated protein kinase/extracellular signal–regulated
kinase (MAPK/ERK) pathway have been shown in nearly half of the cases of Rosai-Dorfman …

Abstract Objectives Rosai-Dorfman disease (RDD) is a rare disorder characterized by the
accumulation of large S100 protein-positive histiocytes that typically exhibit emperipolesis …

Histiocytic neoplasms, including Langerhans cell histiocytosis (LCH), Erdheim-Chester
disease (ECD), and Rosai-Dorfman disease (RDD), present a diagnostic challenge due to …

Objectives To report findings from the 2021 Society for Hematopathology/European
Association for Haematopathology Workshop within the category of B-cell lineage …

Rosai-Dorfman disease (RDD) is an uncommon histiocytic disorder typically involving lymph
nodes and less frequently extranodal tissues. RDD involving the breast is rare and may …