The role of non-invasive respiratory support (high-flow nasal oxygen and noninvasive
ventilation) in the management of acute hypoxemic respiratory failure and acute respiratory …

The current opioid epidemic is one of the most severe public health crisis in US history.
Responding to it has been difficult due to its rapidly changing nature and the severity of its …

We summarise the evidence for medicinal uses of opioids, harms related to the extramedical
use of, and dependence on, these drugs, and a wide range of interventions used to address …

Opioids are widely used as therapeutic agents against moderate to severe acute and
chronic pain. Still, these classes of analgesic drugs have many potential limitations as they …

Opioid Abuse in Chronic Pain — Misconceptions and Mitigation Strategies | New England Journal
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

This book presents 55 clinical cases emphasizing the basic science aspects of pathology
and is “the closest you can get to the wards without seeing patients.” Each case includes an …

Opioid treatment of pain is generally safe with 0.5% or less events from respiratory
depression. However, fatalities are regularly reported. The only treatment currently available …

Buprenorphine is a Schedule III opioid analgesic with unique pharmacodynamic and
pharmacokinetic properties that may be preferable to those of Schedule II full μ-opioid …

Opioid-induced respiratory depression is potentially life-threatening and often regarded as
the main hazard of opioid use. Main cause of death is cardiorespiratory arrest with hypoxia …

The use of opioid analgesics has a long history in clinical settings, although the
comprehensive action of opioid receptors is still less understood. Nonetheless, recent …