Review on Bovine Tuberculosis: An Emerging Disease Associated with Multidrug-Resistant Mycobacterium Species

M Borham, A Oreiby, A El-Gedawy, Y Hegazy… - Pathogens, 2022 - mdpi.com
Bovine tuberculosis is a serious infectious disease affecting a wide range of domesticated
and wild animals, representing a worldwide economic and public health burden. The …

Mycobacterium tuberculosis Transmission in High-Incidence Settings—New Paradigms and Insights

M Coleman, L Martinez, G Theron, R Wood, B Marais - Pathogens, 2022 - mdpi.com
Tuberculosis has affected humankind for thousands of years, but a deeper understanding of
its cause and transmission only arose after Robert Koch discovered Mycobacterium …

[HTML][HTML] Rapid diagnosis of drug-resistant tuberculosis–opportunities and challenges

K Naidoo, R Perumal, SL Ngema, L Shunmugam… - Pathogens, 2023 - mdpi.com
Global tuberculosis (TB) eradication is undermined by increasing prevalence of emerging
resistance to available drugs, fuelling ongoing demand for more complex diagnostic and …

The Mycobacterium tuberculosis genome at 25 years: lessons and lingering questions

BN Koleske, WR Jacobs… - The Journal of clinical …, 2023 - Am Soc Clin Investig
First achieved in 1998 by Cole et al., the complete genome sequence of Mycobacterium
tuberculosis continues to provide an invaluable resource to understand tuberculosis (TB) …

[HTML][HTML] Antibiotic therapy for pan-drug-resistant infections

MA Ozma, A Abbasi, M Asgharzadeh… - Le infezioni in …, 2022 - ncbi.nlm.nih.gov
Antibiotic resistance occurs when microorganisms resist the drugs used against the infection
caused by them and neutralize their effects over time using various mechanisms. These …

Pulmonary Tuberculosis in Children: A Forgotten Disease?

U Pelosi, R Pintus, S Savasta, V Fanos - Microorganisms, 2023 - mdpi.com
Even today, tuberculosis in childhood is a disease that is often undiagnosed and
undertreated. In the absence of therapy with antituberculosis drugs, children in the first years …

Metabolomic analysis of Mycobacterium tuberculosis reveals metabolic profiles for identification of drug-resistant tuberculosis

P Chaiyachat, B Kaewseekhao, A Chaiprasert… - Scientific Reports, 2023 - nature.com
The detection of pre-extensively (pre-XDR) and extensively drug-resistant tuberculosis (XDR-
TB) is challenging. Drug-susceptibility tests for some anti-TB drugs, especially ethambutol …

Mycobacterium tuberculosis Drug Resistance in Ethiopia: An Updated Systematic Review and Meta-Analysis

MA Reta, BA Tamene, BB Abate, E Mensah… - Tropical medicine and …, 2022 - mdpi.com
Background: Tuberculosis (TB) remains a significant global public health issue, despite
advances in diagnostic technologies, substantial global efforts, and the availability of …

[HTML][HTML] The Role of GeneXpert® for Tuberculosis Diagnostics in Brazil: An Examination from a Historical and Epidemiological Perspective

TNS Iúdice, ML da Conceição, AC de Brito… - Tropical Medicine and …, 2023 - mdpi.com
The rapid molecular test (RMT) performed on the GeneXpert® system is widely used as a
control strategy and surveillance technique for tuberculosis (TB). In the region of the …

Evaluation of Xpert MTB/XDR test for susceptibility testing of Mycobacterium tuberculosis to first and second-line drugs in Uganda

A Katamba, W Ssengooba, J Sserubiri, D Semugenze… - PLoS …, 2023 - journals.plos.org
Background Drug-Resistant Tuberculosis (DR-TB) is one of the major challenges to TB
control. Design and methods This was a blinded, laboratory-based cross-sectional study …