Microtubules are essential dynamic polymers composed of α/β-tubulin heterodimers. They
support intracellular trafficking, cell division, cellular motility, and other essential cellular …

Microtubules are key cytoskeletal elements of all eukaryotic cells and are assembled of
evolutionarily conserved α-tubulin–β-tubulin heterodimers. Despite their uniform structure …

The 'tubulin-code'hypothesis proposes that different tubulin genes or post-translational
modifications (PTMs), which mainly confer variation in the carboxy-terminal tail (CTT), result …

Intraflagellar transport (IFT) is a form of motor‐dependent cargo transport that is essential for
the assembly, maintenance, and length control of cilia, which play critical roles in motility …

Microtubules are hollow tube-like polymeric structures composed of α, β-tubulin
heterodimers. They play an important role in numerous cellular processes, including …

Tubulin undergoes several highly conserved posttranslational modifications (PTMs)
including acetylation, detyrosination, glutamylation, and glycylation. These PTMs …

Tubulin posttranslational modifications represent an important mechanism involved in the
regulation of microtubule functions. The most widespread among them are detyrosination …

Intracellular transport depends on cooperation between distinct motor proteins. Two
anterograde intraflagellar transport (IFT) motors, heterotrimeric kinesin-II and homodimeric …

Many primary sensory cilia exhibit unique architectures that are critical for transduction of
specific sensory stimuli. Although basic ciliogenic mechanisms are well described, how …

Primary cilia are small, antenna-like organelles that detect and transduce chemical and
mechanical cues in the extracellular environment, regulating cell behavior and, in turn …