Metabolomic biomarkers in gestational diabetes mellitus: a review of the evidence

S Alesi, D Ghelani, K Rassie, A Mousa - International Journal of …, 2021 - mdpi.com
Gestational diabetes mellitus (GDM) is the fastest growing type of diabetes, affecting
between 2 to 38% of pregnancies worldwide, varying considerably depending on diagnostic …

Regulation of maternal–fetal metabolic communication

CE Bowman, Z Arany, MJ Wolfgang - Cellular and molecular life sciences, 2021 - Springer
Pregnancy may be the most nutritionally sensitive stage in the life cycle, and improved
metabolic health during gestation and early postnatal life can reduce the risk of chronic …

Characteristics and pregnancy outcomes across gestational diabetes mellitus subtypes based on insulin resistance

K Benhalima, P Van Crombrugge, C Moyson… - Diabetologia, 2019 - Springer
Aims/hypothesis This study aimed to determine the characteristics and pregnancy outcomes
across different subtypes of gestational diabetes mellitus (GDM) based on insulin resistance …

Amino acid and lipid metabolism in post-gestational diabetes and progression to type 2 diabetes: A metabolic profiling study

M Lai, Y Liu, GV Ronnett, A Wu, BJ Cox, FF Dai… - PLoS …, 2020 - journals.plos.org
Background Women with a history of gestational diabetes mellitus (GDM) have a 7-fold
higher risk of developing type 2 diabetes (T2D) during midlife and an elevated risk of …

[HTML][HTML] Plasma lipidomics in early pregnancy and risk of gestational diabetes mellitus: A prospective nested case–control study in Chinese women

Y Wang, Y Huang, P Wu, Y Ye, F Sun, X Yang… - The American Journal of …, 2021 - Elsevier
Background Lipid metabolism plays an important role in the pathogenesis of diabetes. There
is little evidence regarding the prospective association of the maternal lipidome with …

An unwelcome inheritance: childhood obesity after diabetes in pregnancy

CL Meek - Diabetologia, 2023 - Springer
Diabetes in pregnancy affects 20 million women per year and is associated with increased
risk of obesity in offspring, leading to insulin resistance and cardiometabolic disease …

[HTML][HTML] Distinct metabolic profile in early pregnancy of overweight and obese women developing gestational diabetes

K Mokkala, T Vahlberg, O Pellonperä, N Houttu… - The Journal of …, 2020 - Elsevier
Background: Reliable biomarkers for gestational diabetes mellitus (GDM) would be
beneficial in the early prevention of adverse metabolic outcomes during pregnancy and …

Molecular biomarkers for gestational diabetes mellitus and postpartum diabetes

W Lu, C Hu - Chinese Medical Journal, 2022 - mednexus.org
Gestational diabetes mellitus (GDM) is a growing public health problem worldwide that
threatens both maternal and fetal health. Identifying individuals at high risk for GDM and …

The birth of cardiac disease: Mechanisms linking gestational diabetes mellitus and early onset of cardiovascular disease in offspring

C Tocantins, MS Diniz, LF Grilo… - WIREs mechanisms of …, 2022 - Wiley Online Library
Cardiovascular disease (CVD) is the biggest killer worldwide, composing a major economic
burden for health care systems. Obesity and diabetes are dual epidemics on the rise and …

A prospective study of early-pregnancy thyroid markers, lipid species, and risk of gestational diabetes mellitus

Y Wang, F Sun, P Wu, Y Huang, Y Ye… - The Journal of …, 2022 - academic.oup.com
Context While the associations between thyroid markers and gestational diabetes mellitus
(GDM) have been extensively studied, the results are inconclusive and the mechanisms …