One in 4 Americans> 40 years of age takes a statin to reduce the risk of myocardial
infarction, ischemic stroke, and other complications of atherosclerotic disease. The most …

Abstract Treatment with statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A
reductase, has proven beneficial preventive effects on cardiovascular events. However …

Since the publication of the 2012 guidelines new literature has emerged to inform decision-
making. The 2016 guidelines primary panel selected a number of clinically relevant …

Background: Cohort studies have reported that midlife high total serum cholesterol (TC) is
associated with increased risk of Alzheimer's disease (AD) in late-life but findings have been …

Aims As the potential impact of statins on cognitive decline and dementia is still debated, we
conducted a meta-analysis of observational studies to examine the effect of statin use on the …

Alzheimer's disease (AD) was used to describe pre-senile dementia to differentiate it from
senile dementia, which develops in the adult age group of more than 65 years. AD is …

Abstract The Canadian Consensus Working Group has updated its evaluation of the
literature pertaining to statin intolerance and adverse effects. This overview introduces a …

Background Worldwide, the prevalence of dementia is increasing and diet as a modifiable
factor could play a role. Meat consumption has been cross-sectionally associated with …

Human longevity has increased dramatically during the past century. More than 20% of the 9
billion population of the world will exceed the age of 60 in 2050. Since the last three …

Background Despite substantial research and development investment in Alzheimer's
disease (AD), effective therapeutics remain elusive. Significant emerging evidence has …