Azomethine imines constitute a versatile class of dipoles that are being increasingly used for
the synthesis of biologically relevant heterocycles. This review details the various reactions …

Spirooxindoles are frequently encountered in the basic skeleton of a diverse range of
natural alkaloids and therapeutically significant molecules. Consequently, the developments …

Allylation of N-unsubstituted isatin N, N′-cyclic azomethine imines with Morita-Baylis-
Hillman carbonates in the presence of 1–10 mol% DABCO in DCM at room temperature …

A novel one-pot N–S bond cleavage of tosyl hydrazone derivatives of isatin and fluorenone
by (het) arynes was discovered. The reaction produced diverse diaryl and heteroaryl-aryl …

The synthesis of dicyclic spiropyridazine oxoindole derivatives by using [3+ 3]-cycloaddition
of N-unsubstituted isatin N, N′-cyclic azomethine imine 1, 3-dipoles was reported. The …

Spiro compounds are a class of naturally occurring organic molecules with a wide broad of
applications in several fields, mainly in medicinal chemistry. Spirooxindoles have been …

Analogies between the mechanisms of electrophilic substitution and nucleophilic
substitution have been discussed. Theoretical calculations, involving aromaticity …

The umpolung Michael addition of isatin N, N′-cyclic azomethine imine 1, 3-dipoles with
chalcones is reported. The reaction could be finished within a very short time (0.3–2 min) …

Summary This Chapter Contains Sections titled: 2+ 2‐Cycloaddition 2+ 3‐Cycloaddition 2+
4‐Cycloaddition Miscellaneous References Tetrafluorothiophene S, S‐dioxide is a potent …