Convalescent plasma therapy for management of COVID-19: Perspectives and deployment in the current global pandemic

N Samad, TE Sodunke, HA Banna… - … and healthcare policy, 2020 - Taylor & Francis
The world is striving against the severe crisis of the COVID-19 pandemic. Healthcare
professionals are struggling to treat their patients based on nonspecific therapies. Amidst …

Antithrombin therapy: Current state and future outlook

GM Rodgers, A Mahajerin - Clinical and Applied Thrombosis …, 2023 - journals.sagepub.com
Antithrombin (AT) is a natural anticoagulant pivotal in inactivating serine protease enzymes
in the coagulation cascade, making it a potent inhibitor of blood clot formation. AT also …

Convalescent plasma is ineffective for covid-19

EB Pathak - Bmj, 2020 - bmj.com
Convalescent plasma generated great enthusiasm in the earliest days of the coronavirus
disease 2019 (covid-19) pandemic because of a plausible mechanism of action, 1 its 100 …

WBC image segmentation based on residual networks and attentional mechanisms

J Wu, X Zheng, D Liu, L Ai, P Tang… - Computational …, 2022 - Wiley Online Library
White blood cell (WBC) morphology examination plays a crucial role in diagnosing many
diseases. One of the most important steps in WBC morphology analysis is WBC image …

Factor XI deficiency: phenotypic age-related considerations and clinical approach towards bleeding risk assessment

AA Barg, T Livnat, G Kenet - Blood, 2024 - Elsevier
Factor XI (FXI) deficiency is a rare bleeding disorder that presents complex challenges in
patient assessment and bleeding risk management. Despite generally causing mild to …

Overestimation of fibrinogen concentration in cryoprecipitate by repeated freeze–thawing with long thawing period as used in the Clauss method

Y Tanaka, T Matsumoto, K Kadoya, Y Shimokaria… - …, 2023 - Wiley Online Library
Background Cryoprecipitate (CRY) is widely used for treating acquired hypofibrinogenemia.
During our study to determine an optimal preparation method, we noticed that the …

Proteomic Characterization of Transfusable Blood Components: Fresh Frozen Plasma, Cryoprecipitate, and Derived Extracellular Vesicles via Data-Independent Mass …

JH Hwang, A Lai, JP Tung, DG Harkin… - Journal of Proteome …, 2024 - ACS Publications
Extracellular vesicles (EVs) are a heterogeneous collection of particles that play a crucial
role in cell-to-cell communication, primarily due to their ability to transport molecules, such …

Blood transfusion trends in the United States: national inpatient sample, 2015 to 2018

R Goel, X Zhu, EU Patel, EP Crowe, PM Ness… - Blood …, 2021 - ashpublications.org
Blood transfusions are among the most common therapeutic procedures performed in
hospitalized patients. This study evaluates contemporary national trends in red blood cell …

Clinical, Laboratory Aspects and Management of Factor X Deficiency

M Menegatti, F Peyvandi - Seminars in Thrombosis and …, 2024 - thieme-connect.com
Coagulation factor X (FX), originally named Stuart–Prower factor, plays a pivotal role in the
coagulation cascade, activating thrombin to promote platelet plug formation and prevent …

Preparation of Cryoprecipitate and Cryo-depleted Plasma for Proteomic Research Analysis

RL Sparrow, RJ Simpson, DW Greening - Serum/Plasma Proteomics …, 2023 - Springer
When frozen plasma is slowly thawed in cold conditions (1–6° C), high-molecular-weight
plasma proteins precipitate forming a concentrate known as cryoprecipitate. The concentrate …